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by Mark Sircus
08 December 2010
from
IMVA Website
Spanish
Version
Did you know that
long-term use of a daily low-dose aspirin dramatically cuts the risk
of dying from a wide array of cancers?
We just heard in the
news that a British research team unearthed evidence that a low-dose
aspirin (75 milligrams) taken daily for at least five years brings
about a 10 to 60 percent drop in fatalities depending on the type of
cancer.
Researchers from Japan’s
National Cancer Center in Tokyo have found that an increased intake
of magnesium reduces a man’s risk of colon cancer by over 50
percent.
Men with the highest
average intakes of magnesium (at least 327 mg/d) were associated
with a 52 percent lower risk of colon cancer, compared to men who
consumed the lowest average intakes.
Published in the Journal
of Nutrition, [1] the research studied 87,117 people with
an average age of 57 and followed them for about eight years.
Dietary intakes were assessed using a food frequency questionnaire.
Average intakes of
magnesium for men and women were 284 and 279 milligrams per day.
Magnesium stabilizes
ATP, [2] allowing DNA and RNA transcriptions and repairs.
[3]
Magnesium repletion produces rapid disappearance of the periosteal
tumors. [4]
Researchers from the
School of Public Health at the University of Minnesota also
concluded that diets rich in magnesium reduced the occurrence of
colon cancer. [5]
And a previous study
from Sweden [6] reported that women with the highest
magnesium intake had a 40 percent lower risk of developing the
cancer than those with the lowest intake of the mineral.
One would not normally think that magnesium deficiency can increase
the risk of cancer yet we will find that just as severe dehydration
or asphyxiation can cause death, magnesium deficiency can lead
directly to cancer. It is known that carcinogenesis induces
magnesium distribution disturbances, causing magnesium mobilization
through blood cells and magnesium depletion in non-neoplastic
tissues.
Magnesium deficiency is
carcinogenic, and in the case of solid tumors, a high level of
supplemented magnesium inhibits carcinogenesis. [7] Both
carcinogenesis and magnesium deficiency increase the plasma membrane
permeability and fluidity.
Anghileri et al. [8],[9] proposed that modifications of
cell membranes are principal triggering factors in cell
transformation leading to cancer. Using cells from induced cancers,
they found that there is much less magnesium binding to membrane
phospholipids of cancer cells compared to normal cell membranes.
[10]
It has been suggested that magnesium deficiency may trigger
carcinogenesis by increasing membrane permeability. [11]
The membranes of magnesium-deficient cells seem to have a smoother
surface than normal and decreased membrane viscosity, analogous to
changes in human leukemia cells. [12],[13]
There is drastic change
in ionic flux from the outer and inner cell membranes (higher Ca and
Na, lower Mg and K levels) both in the impaired membranes of cancer
and of magnesium deficiency.
And we find that lead (Pb)
salts are more leukemogenic when given to magnesium-deficient rats
than when they are given to magnesium-adequate rats, suggesting that
magnesium is protective. [14]
The School of Public
Health at the Kaohsiung
Medical College in Taiwan found that magnesium
also exerts a protective effect against gastric cancer,
but only for the group with the highest levels. [15]
According to the
National Foundation for Cancer Research, the value of minerals as
part of an anticancer diet is frequently overlooked.
However, minerals can
play a vital role in fighting cancer. Several studies have shown an
increased cancer rate in regions with low magnesium levels in soil
and drinking water. In Egypt the cancer rate was only about 10
percent of that in Europe and America. In the rural fellah it was
practically non-existent. The main difference was an extremely high
magnesium intake of 2.5-3g in these cancer-free populations, ten
times more than in most western countries. [16]
Data suggests that the same holds true for selenium; a diet rich in
selenium protects against cancer of the stomach, breast, esophagus,
lung, prostate, colon, and rectum.
According to Dr.
Harold Foster, death rates in the U.S. for cancer are lower when
blood selenium levels are high. Those who have studied geographical
differences have seen that in low-selenium regions, higher death
rates occurred from malignant lymphomas and cancers of the tongue,
esophagus, stomach, colon, rectum, liver, pancreas, larynx, lung,
kidneys, and bladder.
In addition, cancer patients with low selenium
levels tend to have a wider spread of the disease, more recurrences,
and they die sooner. [17]
In China, where the selenium levels in the soils varies much more
dramatically than in the United States and the population is less
mobile, an ecological study in 1985 showed dramatic results in
linking cancer with selenium deficiencies.
Dr. Shu-Yu Yu
measured the selenium content of blood stored in blood banks in 30
different regions in China and classified the regions as high
selenium, medium selenium, and low selenium. They then compared
death rates from cancer to the selenium rates and found there was an
exact correlation. In the low selenium classification, three times
as many people died from cancer as in the high selenium
classification.
The West African country of Senegal is dominated by high
concentrations of selenium in the soil and thus in their foods, and
as expected, Senegalese males had the world’s lowest rates for
cancer of the trachea, bronchus, lung, stomach, and colon, the
fourth lowest for prostate cancer, and sixth lowest for esophageal
cancer.
Senegalese women had the
lowest incidence of cancers of the trachea, bronchus, lung,
esophagus, stomach, and colon, and second lowest for breast cancer,
and fifth lowest for cancer of the uterus.
Selenium helps stop damaged DNA molecules from reproducing, meaning
it acts to prevent tumors from developing.
“It contributes
towards the death of cancerous and pre-cancer cells. Their death
appears to occur before they replicate, thus helping stop cancer
before it gets started,” says Dr. James Howenstine in A
Physician’s Guide to Natural Health Products That Work.
A 1996 study by Dr.
Larry Clark of the University of Arizona showed just how
effective selenium can be in protecting against cancer.
In the study of 1,300
older people, the occurrence of cancer among those who took 200
micrograms of selenium daily for about seven years was reduced by 42
percent compared to those given a placebo.
Cancer deaths for those
taking the selenium were cut almost in half, according to the study
that was published in the Journal of the American Medical
Association on December 25, 1996.
In addition, the people
who had taken selenium had 63 percent fewer prostate cancers, 58
percent fewer colorectal cancers, 46 percent fewer lung cancers and
overall 37 percent fewer cancers. Selenium was found to reduce the
risk of lung cancer to a greater degree than stopping smoking.
[18]
Much of the same can be said about the cancer prevention and
treatment possibilities of
iodine and
sodium bicarbonate. Few people
know that at least one in every five cancers is caused by infection
and that is discounting the theory that cancer is a fungus.
To alert public opinion
to this little-known fact, a massive campaign by the
International Union against Cancer (UICC) on the theme of
prevention updates us on the viruses and bacteria that can lead to
the deadly disease.
"Of the 12 million
people who are diagnosed with cancer each year, around
20
percent of cases can be attributed to viral and bacterial
infections that either directly cause or increase the risk of
cancer," says Professor David Hill, UICC president.
Iodine can be taken in
high dosages forever since the body needs iodine, whereas it does
not need aspirin.
Iodine is anti-viral and
antibacterial as well as a prime substance that can be used against
fungus infections with the mighty mallet of baking soda helping
tremendously in this regard.
Minerals are and have always been the primary medicinals that we
have to both prevent and treat cancer, and it should be obvious that
they are safer to use than aspirin, which is actually quite
dangerous to use over the long-term.
I recommend that
magnesium
chloride be chosen as the best magnesium salt and that it should be
used both transdermally and orally.
Pure magnesium oil with
extremely low levels of mercury is the obvious choice - one should
avoid using products sourced from the Dead Sea and from the Great
Salt Lake in Utah since both areas are very high in mercury
contamination.
End Notes
[1] “High dietary
intake of magnesium may decrease risk of colorectal cancer in
Japanese men” Volume 140, Pages 779-785 Authors: E. Ma, S.
Sasazuki, M. Inoue, M. Iwasaki, N. Sawada, R. Takachi, S.
Tsugane, Japan Public Health Center-based Prospective Study
Group.
[2] Mg2+ is critical for all of the energetics of the cells
because it is absolutely required that Mg2+ be bound (chelated)
by ATP (adenosine triphosphate), the central high energy
compound of the body. ATP without Mg2+ bound cannot create the
energy normally used by specific enzymes of the body to make
protein, DNA, RNA, transport sodium or potassium or calcium in
and out of cells, nor to phosphorylate proteins in response to
hormone signals, etc. In fact, ATP without enough Mg2+ is
non-functional and leads to cell death. Bound Mg2+ holds the
triphosphate in the correct stereochemical position so that it
can interact with ATP using enzymes and the Mg2+ also polarizes
the phosphate backbone so that the ‘backside of the phosphorous’
is more positive and susceptible to attack by nucleophilic
agents such as hydroxide ion or other negatively charged
compounds. Bottom line, Mg2+ at critical concentrations is
essential to life,” says Dr. Boyd Haley who asserts strongly
that, “All detoxification mechanisms have as the bases of the
energy required to remove a toxicant the need for Mg-ATP to
drive the process. There is nothing done in the body that does
not use energy and without Mg2+ this energy can neither be made
nor used.” Detoxification of carcinogenic chemical poisons is
essential for people want to avoid the ravages of cancer. The
importance of magnesium in cancer prevention should not be
underestimated.
[3] Magnesium has a central regulatory role in the cell cycle
including that of affecting transphorylation and DNA synthesis,
has been proposed as the controller of cell growth, rather than
calcium. It is postulated that Mg++ controls the timing of
spindle and chromosome cycles by changes in intracellular
concentration during the cell cycle. Magnesium levels fall as
cells enlarge until they reach a level that allows for spindle
formation. Mg influx then causes spindle breakdown and cell
division.
[4] Hunt, B.J., Belanger, L.F. Localized, multiform, sub-periosteal
hyperplasia and generalized osteomyelosclerosis in
magnesium-deficient rats. Calcif.Tiss.Res. 1972; 9:17-27.
[5] American Journal of Epidemiology (Vol. 163, pp. 232-235).
[6] Journal of the American Medical Association, Vol. 293, pp.
86-89.
[7] Durlach J, Bara M, Guiet-Bara A, Collery P. Relationship
between magnesium, cancer and carcinogenic or anticancer metals.
Anticancer Res. 1986 Nov-Dec;6(6):1353-61.
[8] Anghileri, L.J. Magnesium concentration variations during
carcinogenesis.Magnesium Bull.1979; 1:46-48.
[9] Anghileri, L.J., Collery, P., Coudoux, P., Durlach, J.
(Experimental relationships between magnesium and cancer.)
Magnesium Bull. 1981; 3:1-5.
[10] Anghileri, L.J., Heidbreder, M., Weiler, G., Dermietzel, R.
Hepatocarcinogenesis by thioacetamide: correlations of
histological and biochemical changes, and possible role of cell
injury. Exp. Cell. Biol. 1977; 45:34-47.
[11] Blondell, J.W. The anticancer effect of magnesium.Medical
Hypothesis 1980; 6:863-871.
[12] Whitney, R.B., Sutherland, R.M. The influence of calcium,
magnesium and cyclic adenosine 3’5’-monophosphate on the mixed
lymphocyte reaction. J. Immunol. 1972; 108:1179-1183.
[13] Petitou, M., Tuy, F., Rosenfeld, C., Mishal, Z., Paintrand,
M., Jasmin, C., Mathe, G., Inbar, M. Decreased microviscosity of
membrane lipids in leukemic cells; two possible mechanisms.Proc.
Natl. Acad. Sci. USA 1978; 75:2306-2310.
[14] Hass, G.M., McCreary, P.A., Laing, G.H., Galt, R.M.
Lymphoproliferative and immumunologic aspects of magnesium
deficiency. In Magnesium in Health and Disease (from 2nd Intl Mg
Sympos, Montreal, Canada, 1976), b Eds. M. Cantin, M.S. Seelig,
Publ. Spectrum Press, NY, 1980, pp 185-200.
[15] Yang CY et al. Jpn J Cancer Res.1998 Feb;89 (2):124-30.
Calcium, magnesium, and nitrate in drinking water and gastric
cancer mortality.
[16] MAY 19, 1931, Dr. P. Schrumpf-Pierron presented a paper
entitled "On the CauseOf the Rarity of Cancer in Egypt," which
was printed in the Bulletin of the Academy of Medicine, and the
Bulletin of the French Association for the Study of Cancer in
July, 1931.
/www.mgwater.com/rod02.shtml
[17] Foster HD. "Landscapes of Longevity: The
Calcium-Selenium-Mercury Connection in Cancer and Heart
Disease," Medical Hypothesis, Vol. 48, pp 361-366, 1997.
[18] Clark LC.The epidemiology of selenium and cancer. Fed Proc
1985; 44:2584-2590.
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