by Jesús Pérez

received by Email through A.K.

on January 29, 2009


Dear Sirs and Madams,

I take the liberty of attaching the theory I have created, building on 20 years of empirical research on the possible causes of viral and bacterial infections. To express the results of my experience in a nutshell: I have come to the conclusion that acid-basic balance in our cells is at the root of a state of health or of illness of a human being.


As I do not have the resources or the background to follow up my ideas scientifically, my aim in contacting the Foundation is to ask for an opportunity to be taken seriously by the scientific community, and for contacts with researchers that might look into the notions expressed in the attached outline. I am not asking the Foundation for money but only help to be able to expose some ideas that in many ways are contrary to current medical practice.

Yours sincerely
Jesús Pérez

Health or illness might depend on the outcome of a struggle between active substances (enzymes) against substrates of low solubility or insoluble (inhibitory agents) in a blood circuit with acid-basic balance (neutral pH). In other words, they depend on the struggle between slightly alkaline native proteins against denatured acid proteins.

I have spent part of my life studying the origin of AIDS, Cancer and other illnesses and I have come to the conclusion that at the root of these diseases are the manipulation of foodstuffs and unbalanced diets which produce acidosis, which in turn blocks oxidation, combustion and excretion in the cells.

The inhibition and de-inhibition which takes place continually in the human body alters the dynamic balance in the function of the cells to manage a perfect colloidal dispersion of its molecules, and this causes the development of diseases.

Drawing on my experience, I would like to demonstrate to what degree our diet influences our state of health.


Endogenous viruses are denatured proteins

The origin of endogenous viruses is the following: we humans, through our intake of food, introduce into our bodies denatured proteins, which we should consider exogenous. Ribosomes are in charge of synthesizing these exogenous proteins, causing mutations, which are structural changes that transform them into endogenous proteins. When recurrent mitochondrial mistakes occur they can turn into viral proteins, such as HIV.

Viruses are ARN or ADN nucleic acid particles united to proteins. In the synthesis of new proteins more personal phenomena intervene within the body, as due to hereditary mechanisms or those derived from the specific biochemical setup of an individual only those proteins are synthesized that are specific to each human being. Hereditary genes have the clue to the fact that they are “individual”.

The unique composition of the proteins in all organisms allows them to distinguish, and also to fight against all strange, denatured, proteins.


This is the basis of all mechanisms of immunological defense, and for this reason it is logical to think that the HIV virus is endogenous and not exogenous. This is to say, the endogenous virus is created from a denatured protein because the protein causes mitochondrial errors that give rise to successive mutations of the protein synthesized by the ribosomes, converting it into a viral protein.

At present, new theories are being formulated, but no solutions are found for AIDS. In spite of the alarming reports from the WHO, where serious contradictions are found within the very same scientific community, and in spite of the sterility of its results, scientists deny that the therapies imposed today are a serious error, as they are all geared towards keeping the AIDS virus to penetrate the cell.

Medical scientists believe that infectious diseases are caused by viruses or bacteria that accidentally penetrate the human body, mutating, multiplying, and also being transmitted by contagion from one person to another.

These researchers, in order to prevent and fight against such diseases, have been looking for methods of immobilizing enzymes (directed mutagenesis), vaccines, antibiotics, inhibitors, denatures substances, etc. giving rise to chemical warfare against the different micro-organisms that inhabit our body.


Medical science today is extremely demanding and it does not accept as valid any new theories, even if they might look promising, if they have not been tested and confirmed by different groups of researchers.

For medical scientists, to claim that the HIV virus is endogenous is tantamount to being heretical, because, according to the same source, it has been proven that it is exogenous, even if nobody has been capable of demonstrating what its origin is.

The erroneous belief that viruses cause the disease and that they should be controlled or eliminated is widespread, just as the narrowness of mind of those to whom any other idea that might appear in relation to this topic, such as the one that the badly nourished cell causes the disease and as a consequence transforms exogenous protein into endogenous viral protein, thus developing an infection.


This is to say, first the cells become diseased and then the virus appears. For this reason, the virus is not the cause of the infection. This same procedure applies in the cancer of the uterus.

The papilloma virus (HPV) has no direct relationship with the cancer and it is not the cause of cancer of the uterus.


The Papilloma Vaccine Fraud

Vaccinating against HPV is not just medically useless, it is also harmful to the health of adolescents and young women. Scientists do not know why viruses are reactivated and cause permanent infections. Actually, no-one has, as yet, found the way to kill any virus.

Luc Montagnier, Head Researcher on Viral Oncology at the Pasteur Institute, has publicly said that his scientific obsession,

“is to demonstrate that there is something more than HIV in the cause of the disease”.

According to a declaration by the French scientist during his contribution to the IX International Conference on AIDS in Berlin,

“HIV is not the only responsible for the syndrome, and it even does not attack nor destroy the cell of the immune system. It can happen that, at a certain moment, not even HIV plays any role at all. Only the joint action of one or several co-factors can explain the process of cellular apoptosis that brings about the destruction of a great number of lymphocytes”.

Kary Mullis, winner of the Nobel Chemistry Prize, at a congress in Toledo (Spain) in April 1994, denied that HIV is the cause of AIDS:

“I don't know how to explain this in a few words, but I have dates that confirm that AIDS is not an infectious disease, it is not caused by the virus”, the scientist said.


  • Inhibitory action: If non-natural substrates that reduce the enzyme's activities are added to an enzymatic system, this system is said to have been inhibited, and the substrate thus used is called an inhibitor.

    Many inhibitors are agents that denature the enzymes, as the latter are protein molecules and they are sensitive to many agents, especially chemical ones. These agents that inhibit enzymatic activity act on practically all enzymes, which shows that their action is not specific, but that they act on all protein molecules. If there is a large amount of natural substrate, the inhibitor is dominated and displaced, and the natural substrate enters the active areas of the enzyme to allow the catalytic activity to recommence.

    None of the viruses that affect humankind have been found to have a viral origin, because the viruses live and develop within our organism and become manifest only when they have been induced through the presence of denatured substances to a mutation of its own microorganisms.

  • Spontaneous mutations: They are the result of normal cell activity, or of its interactions with its natural medium. Most of them are caused by errors in the replication process, or in the process of ADN repair or re-combination. (In short, they would be those mutations that are not caused experimentally).

  • Induced mutations: They are those caused by previous experimental alteration of ADN, directly or indirectly, through physical or chemical agents called mutagens.

  • Suppressing mutation: is the mutation that reduces the performance of the mitochondria, due to the fact that, apart from its suppressing capacity, it induces errors in normal mitochondrial RNA readings.

Mutations are specific genetic defects, that is, molecular alterations of genetic material. Such mutations cause alterations in enzymes and other proteins.

How many protein mutations are necessary for them to become viral proteins?

In order to know when such mutations or changes are carried out it is necessary to find out which are the denatured substances that produce such transformations, and it is obvious that nutrition malpractice should be partly to blame. Nutrition is involved in the change of the molecular structure of our microorganisms causing them to mutate.


This action of transformation of the microorganism into HIV virus can only take place in those specific cells that are genetically predisposed. The substrates produced contribute to a depression of spinal marrow, affecting the quantitative and qualitative production of lymphocytes. This is the reason why the origin of AIDS can be explained simply in terms of “immunitary overload", i.e. a progressive self-poisoning of the organism.

If, as seems to be the case, the so-called degenerating diseases are really mitochondrial diseases insolubly bound to the processes of "general debilitation" which opens the door to many other diseases, it would be adequate to consider them the most radical of all diseases, "the mother of all diseases".


It is an attack on our genetic material due to acid-alkali imbalance.


The diseases caused by damage to the mitochondrial genome have in common that they are produced by a deficiency in the ATP biosynthesis, due to the fact that all the information contained in this DNA is directed towards synthesis of proteins contained in the Oxphos system. Such diseases appear in different forms and can affect all our organs and tissues, as ATP synthesis takes place in all of them. They can appear with certain clinical, morphological and biochemical aspects that give rise to syndromes.


Mitochondrial malfunction can also contribute to the syndrome of immunodeficiency.

The mitochondria deteriorate as a consequence of an accumulation of mutations. When the mutated DNA passes a threshold it will show a pathogenic phenotype, i.e. if PAT production falls below the necessary minimum for the performance of the tissues, due to a defect in the proteins encoded in mitochondrial DNA, an illness will appear.

Mitochondrial toxicity is a kind of damage that will decrease the number of mitochondria. If there are very few mitochondria in the cell, it will stop working adequately, or it will not function at all. The mitochondria deteriorate as time passes as a consequence of an accumulation of mutations.

In October 1993, a research group in Kenya and Canada published the results of an experiment consisting in maintaining 424 prostitutes in Nairobi under observation for 10 years. In spite of having carried out some 500 sexual encounters with HIV positive men, they had not been infected by the virus. This study, published in the journal Lancet, suggests that the prostitutes had a natural immunity against the HIV virus.

Two years later a group of British physicians published their research in the journal Nature Medicine.


They had found, in a group of Gambian prostitutes, “a strange immunity against the AIDS virus”. The researchers found that the women had –T cells, which kill those cells that have been infected by the virus. The Institute of Molecular Medicine at Oxford explained that the high level of lymphocytes –T was the reason for their immunity.

Currently I ignore whether the study was followed up or whether both projects have been abandoned, and if the prostitutes still have not been infected by the HIV virus. In my opinion, the result of this research throws doubt on the notion that HIV is contagious, and leads me to believe that it is developed within those people who are genetically predisposed, as a consequence of sustained imbalance in their diet (i.e. that it is endogenous).

There are HIV positive patients who through the protease inhibition treatment have developed diabetes, that is, first they have been HIV infected and then they have become diabetic but,



This would confirm that there is no diabetic who has contracted HIV.


The amino acids are the basic elements of growth of all live beings. When a human, or a HIV, cell multiplies, the genetic code is “read”. Amino acids are created according to the genetic code and join together in proteins in order to create the new cell, or new virus.

If a constant inhibitory diet has caused progressive changes in the delicate biological balance of the human being, micro-organisms have developed in the body, acting like endogenous mutagenic agents.

Researchers at the University of North Carolina and the Department of Agriculture in the United States have established, for the first time, a relationship between deficiencies in nutrition and the development of dangerous viral mutations.


The results of this research were published in the journal Nature Medicine.

“Through further experiments, the American research group wishes to find out whether dietary problems are a factor in the development of illnesses such as the flu, hepatitis, meningitis, and other diseases that affect humans”.

Bad dietary habits gave rise, initially, to the appearance of an incomplete virus, which, as it was not detected by analyses, was supposed to be hidden in lymphatic ganglia.


This is not really so, because as the same type of diet was continued the constituent material is the same, but the structural substrates which are a result of new protein synthesis will continue creating, developing and completing HIV virus.

The genetic variants created new viruses of different molecular structure, that is, endogenous viruses of new design, introduced through chemical reactions of the substrate provided by bad dietary habits. They accepted in their bases new molecular atoms, changing their structure, and giving rise to the development of new viruses that were more resistant to new structural rupture, staying inside our body for the rest of our lives.

The cure of AIDS depends on whether the lymphocyte cells perform in their optimum pH.

It is a source of preoccupation that the medical profession refuses to accept this theory, or at least to take it seriously, even though it has not been capable of demonstrating the origin of AIDS scientifically.

Enzymes typically present a maximum of catalytic activity at a specific pH. This value is called optimum pH.

Because enzymes are proteins, any sudden change in pH can alter the ionic character of amino and carboxyl groups in the protein surface, thus affecting the catalytic properties of an enzyme. If the pH is high or low denaturing of the enzyme can follow, and consequently is de-activation.

In December 1995, the use of the first inhibitor of HIV viral protease was approved. Other inhibitor followed, and in mid-1996 a new generation of inhibitors of viral inverse transcriptase, intended to inhibit enzymatic functions, appeared on the market. I believe it is a serious error to try to invert enzymatic functions established by the very nature of a living organism.


That is, to keep the active principles (enzymes) from carrying out their proper mission, which is activation, as they are the protein catalysts that regulate the speed with which physiological processes take place. As a consequence, the deficiencies in enzymatic function cause pathologies, secondary effects, and collateral damage through the action of inhibitors that have drastic physiological consequences due to the impairment of enzymatic activity, even if in only one single enzyme.

The enzymes protease and inverse transcriptase are very sensitive to pH change and deviation, even if only few decimal points above or below the optimum pH. Such changes can affect their activity drastically and even small changes can cause denaturing of the protein. Balanced “live” foodstuffs contribute to maintaining intracellular pH stable (they are physiological dampers).

In the view of medical researchers, if the inhibitors of protease and transcriptase are not effective, the enzymes will be activated and the inhibition will not be concluded, the substrate is not maintained within the cell to block it and the enzymes will be able to “read” the viral genetic code and give rise to the new substrate, which would be the “Troyan horse” of the infection.

If the inhibitors manage to block defending cells, on the one hand, their function is also blocked, debilitating the immune system, and, on the other hand, we have to ask ourselves: What is to be done with the accumulated and multiplied viruses in order for them not be absorbed by the inactive cells? And, if they multiply, which they are bound to do: Which is the providing source? The blocked cells cannot replicate new viruses.

Medical scientists, in this case, drastically separate from the bases set by scientists experts in pH performance and enzymology, and do not take into account that the effect of the co-factors in enzymatic activity are given by the substances provided in the diet.


They do not take into account that the influence the diet can have on the amount of inhibitors, nor on the role physical activity, increase of temperature and change of pH, which will make them lose effectiveness and give rise to new and more resistant mutations. Native proteins can provide the essential amino acids to the protease and transcriptase and de-block them.

When the sperm fertilizes the ovum, its mitochondria remain outside the ovum, the fertilized zygote inherits only the mother’s mitochondria. This inheritance from the mother crates a family tree that will not be affected by the re-combinations of genes that take place between the father and the mother. For this reason, Magic Johnson, famous basketball player and HIV positive, has not infected his wife not their daughter.

The correct therapy would be to dynamize the lymphocyte cells, with the help of new enzymatic substance (active principles) that will help phagocyte the viruses, and thus process the denatured substrate in a function assisted by oxidation and reduction (the giving up of protons). The virus would mutate into structure of lower molecular magnitude and become negativized.

The Russian Metchnikoff, Nobel prize laureate in 1908, thought that the microorganisms were phagocyted by special cells (theory of cellular immunity).

The British scientist Wright adopted this theory and said,

“The power of phagocytosis of the defending cells depends on its function by active substances” and he used the word OPSONINE (OPSONÔ: “I prepare food for”).

Evidently enough, any therapy applied, to be successful, will have to be combined with the administration of active substances in certain amounts. If this is missing it will cause a reduction in immune competence.

It is not the same to say:

  • “research should be centered on finding out which are the active principles that can help enzymatic function in order to regenerate the life of the cell”

  • as to say “research should be geared towards finding out which are the active principles that can help enzymatic function, in order to regenerate life in the cell”,

  • or to say “research should go in search of inhibitory agents of cellular activity, in order to stop the mission that nature itself has given it”

This would lead to a programming of an early cellular death.

It is difficult to understand why some researchers recognize that the enzymes are essential for the life of the cells of the receiving organ, and, at the same time, other medical researchers devote all their efforts to trying to find the “substrate” (exogenous) which is most effective in paralyzing the natural function that the enzyme is in charge of.

  • Why not consider the danger of introducing a killing agent in the organism?

  • Wouldn’t this develop the disease instead of creating immunity against it?

It is the obligation of doctors to maintain life and cellular activity allowing the arrival of native proteins to the cell, in order to make it work normally and, especially in the case of those who are HIV positive, as they are even more in need to maintaining the activity of those cells in charge of contributing to immune-competence.

If the cells do not obtain sufficient energy through cellular breathing, oxygen deficit can generate lactic acid as a waste product.


HIV positive people should know which are the symptoms of lactic acidosis, as it is and effect that can be deadly.



It is difficult for me to understand how, on the one hand, some researchers say that we should potentiate the selective creation of defenses in our immunitary system, and on the other hand, medical scientists are in favor of the administration of an inhibitory agent in order to inactivate the receiving cell (which is also the defending cell), blocking it with a view to avoid replication of the virus.


The paralysis of the phagocyting action of the substrate of the defending cell leads to the programmed death of it (cellular apoptosis). Can it be beneficial to program the killing of lymphocyte cells, defenders of the organism, deliberately introducing the killer into the body?

As differences in opinion exist it is necessary to study this topic in depth with a view to find the truth of the matter.



For repair of damaged mitochondrial and nuclear DNA to take place it is mandatory to make the specific cell work in its optimum pH. If this condition is not present it will not be possible to stop the disease.

The optimum pH, or pH of maximum activity, is found around 6.5, and therefore, if it is lowered to 3 with an acidizing agent the unwanted enzyme will become inactive. If we look at the labels of our foodstuffs we will certainly find some acidizing agent in most of them, such as citric acid, which is used to this end.

Adequately fed cells will create immunity and give to the organism the inherent capacity of curing itself.


Some common pH values



Lemon juice






Orange juice or apple




Bottled water






Saliva (cancer or AIDS patients)

4,5 to 5,7

Milk (fresh from the animal)

6,8 a 7,0

Human saliva


Blood, kidney, lung

7,35 to 7,45

Sea water





Acid-basic balance in the organism: this is the clue to health
The balance between acids and alkaline substances in the body is critical for its good health. It is not possible to think seriously about individualizing a diet without considering the effect on pH balance in the body.


We are constantly generating acid waste in the metabolism that should be neutralized or excreted for life to be possible. Human beings, therefore, need a constant intake of alkaline food in order to neutralize this constant acid generation. Our life and health depend on the physiological power to maintain the pH in our blood at around 7.35.

All live beings regulate their pH strictly in their intra and extracellular solutions. The variation in the acid-basic property can be seen reflected in the modulation of enzymatic speed and, in humans, in the acidosis produced by acids resulting from metabolism. This can cause cellular damage and death below pH 6.8, as can be seen in diabetes.

If the pH in a human being varies below 7.35-7.45 the diet should be strictly controlled.

pH in the saliva offers a way to evaluate the global pH balance in the body. Saliva pH should be neuter, and due to its HCO3- contents it has acid-neutralizing properties, and thus it plays an important part in the hygiene of the mouth. Furthermore, the saliva has other important roles.

Saliva pH is an indicator of the alkaline reserve in the body and of cellular pH condition. The normal saliva pH should vary around 7.0 - 7.3, any other value being an indication of an illness.

Virtually all degenerative diseases, including cancer , heart disease , osteoporosis, arthritis , kidney and gall stones, and tooth decay are associated with excess acidity in the body. Practically all degenerative illnesses such as cancer, heart disease, osteoporosis, arthritis, kidney, liver and lung diseases, diabetes and caries are associated with an excess of acidity in our body.

Acid-basic stability in the cellular tissue is an important factor for health. Important deviations, produced in extreme situations during serious illnesses are the cause of medical emergencies.

All disease symptoms can be reversible if very acid foods and beverages are suppressed in our diet, and such symptoms will be reactivated if they are consumed again.


Adequately fed cells will create immunity and will give to our organism the inherent capacity to cure itself.

Health is not something we should just dream of; it is something that the human species can attain if the acid-basic balance is not disturbed. A diet that in principle respects a neuter pH, not only will avoid illnesses, but it will also cure already contracted diseases.

From the above, the basic function of pH regulation in biological systems should be clear.


I acknowledge the important work by scientists studying the pH (acid-basic balance) and enzymology. Without their magnificent research and publications I would never have been able to associate my empiric research with scientific research.


I believe that through empiric study popular science can be connected to scientific knowledge.










Correspondence With the 'Bill & Melinda Gates Foundation'

Dear Mr. Perez,

Thank you for contacting the Bill & Melinda Gates Foundation.

While we appreciate how important your request is, unfortunately, it is not within the current giving priorities of the foundation. To remain focused on these priorities, we must decline many worthwhile requests, leaving other donors to support these causes.


The foundation’s Global Health Program focuses on reducing the disease burden in the developing world, with efforts concentrated in:

  • the prevention of and vaccine development for infectious diseases such as HIV/AIDS, tuberculosis, and malaria, as well as others that affect historically underserved populations

  • the development, use, and sustainability of diagnostic tools and technologies

  • maternal, reproductive, and child health

  • advocacy for raising awareness and promoting leadership for these issues

For more information about the foundation’s Global Health Program, please visit

We appreciate your commitment to this work and wish you great success with your endeavors.


Stephanie Jones
Bill & Melinda Gates Foundation


I have received the recent above reply from the Foundation with surprise and dismay.


In my message I very clearly indicated that I am not interested in receiving funding from you, but to find correspondents that might help me to corroborate my ideas with respect to the origin and development of some of the serious illnesses humankind suffers from.


I cannot understand why research of such importance has not even sparked a minimal interest on the part of the Foundation.


I regret to insist on asking for your attention to my ideas, that, even if they go in directions opposite to official research, at least merit to be investigated.

I insist: VIH is not the cause of AIDS infection, and for this reason researchers have not been able to find an effective vaccine. There are several questions which still have not received any answer, such as:

  • Why is there not a single diabetic in the whole world who has been infected with VIH?

  • Why are there many heterosexual couples where one is HIV-positive and the other one is not, who maintain sexual relations and there has been no contagion?

  • Why are there new-born babies of HIV-positive mothers who negativize without treatment?

  • What about the HIV-positive who have received spinal core transplant, and who have negativized?

  • What about the case of the homosexual patients in Los Angeles and San Francisco, California, who supposedly contracted the illness through sexual relations, and nothing was said about the drug called “POPERS” which might have caused damage to the spinal core and therefore has affected the lymphocytes, transforming their molecular structure into viral protein (VIH)?

  • Would it not be of interest to find the answer to such vital questions?