by Mark Sircus

from WinningCancer Website

Spanish version






Contemporary oncology is incapable of giving us the answers and the necessary therapy for cancer patients.


Thus it is our moral and ethical obligation to try to find the best solutions for the gravest and most painful disease of our time without them. This book is going to come as a shock to many doctors and people. Without a doubt the ideas inside will be resisted, but in the end resistance is useless. When it comes to sodium bicarbonate in medicine it is an open and shut case. It is already in wide use and has been for decades!

In relation to bicarbonate, millions of people in the world either consume bicarbonate ions in drinking water or have been treated clinically with bicarbonate in hospitals, medical centers, or emergency units for the prevention and treatment of clinical acidosis as well as numerous other conditions.


Sodium bicarbonate helps to save countless lives every day. It is also found in the corridors of orthodox oncology where it is used to keep the toxic chemotherapy agents from killing people too quickly.

Sodium bicarbonate is the time honored method to 'speed up' the return of the bodyís bicarbonate levels to normal. Bicarbonate is inorganic, very alkaline and like other mineral type substances supports an extensive list of biological functions. Sodium bicarbonate happens to be one of our most useful medicines because bicarbonate physiology is fundamental to life and health.


So helpful and elementary itís even instrumental in helping sperm swim up and enter the cervical canal.1


Like magnesium chloride administration possibilities are versatile:

  • intravenous

  • oral

  • transdermal

  • via catheter

  • it can be vaporized directly into the lungs

  • can be used in enemas and douches

This book is about the application of the least expensive, safest and perhaps most effective cancer medicine there is.


In this very first chapter enough information is presented to convince doctors and patients alike to take or prescribe water with dissolved sodium bicarbonate. By the time one finishes this book it is my belief that most cancer patients will need no more convincing. No more than a thirsty person needs convincing to swallow down water when coming out of the dry desert.

Sodium bicarbonate cancer treatment focuses on delivering natural chemotherapy in a way that effectively kills cancer cells while dramatically reducing the brutal side effects and costs experienced with standard chemotherapy treatments. The costs, which are a factor for the majority of people of this particular treatment, are basically zilch.


Thatís the only problem with this treatment - it is too cheap. No one is going to make money from it so no one will promote it. Those that do will be persecuted for it. The trouble with doing new studies on bicarbonate is that they are expensive and no drug company is going to fund a study when they can't profit from the treatment.

For one pound of sodium bicarbonate from one of the best sources (guaranteed aluminum free) is $2.61 plus shipping. At the supermarket you can get it even cheaper.


For $2.61 or less one has a nothing-to-lose-everything-to-gain-cancer-treatment. None of us dreamed that sodium bicarbonate is already part of orthodox oncology and is included in many chemotherapy protocols to protect the patientís kidneys, hearts and nervous systems. Now we find out on top of everything else that bicarbonate is also a world class anti-fungicide and could be responsible for the few cures allopathic oncology manages to come up with.

You will also be given lots of fluids (as a drip) and a drug called mesna with your cyclophosphamide to help prevent bladder irritation. Sodium bicarbonate will be given to you Ė usually as a drip Ė before and during your methotrexate treatment, to help protect your kidneys.2

This book puts oncologists in a very compromising situation.


They are using extremely dangerous poisons and bicarbonate at the same time claiming it is the poisons that are helping when this book is more than suggesting it is the bicarbonate that is doing the heavy work. Worse for them, there are no studies separating the effects of bicarbonate from the toxic chemotherapy agents nor will there ever be.


Administration of some forms of chemotherapy without bicarbonate would probably kill patients on the spot.

Most thought it was pretty strange when Dr. Tullio Simoncini showed up on our medical radars. He is the oncologist from Rome who pointed to using bicarbonate as a main line cancer treatment and he was persecuted for it. Yet he has stood firm and continues to travel the world teaching doctors about the anti-cancer properties of sodium bicarbonate.

Sodium bicarbonate is one of the oldest workhorse medicines. So solid is bicarbonateís position in orthodox oncology it would probably be considered malpractice to apply most forms of chemotherapy without it.


It is commonly used prior to, during, and after application of chemotherapy.3 Some studies actually have already shown how manipulation of tumor pH with sodium bicarbonate enhances chemotherapy 4 again pointing to the possibility that bicarbonate is the main chemo agent saving people from their cancers.

Since the very beginning sodium bicarbonate has been used with the premier chemotherapy agent made from mustard gas.


Mechlorethamine also known as chlormethine, mustine, nitrogen mustard and HN2 and sold under the brand name Mustargen was the prototype anticancer chemotherapeutic drug. Use of mechlorethamine gave birth to the field of anticancer chemotherapy.


Without baking soda orthodox oncology would never have been able to establish itself for all their patients would probably have died. These chemo drugs are an analogue of mustard gas and were derived from chemical warfare research.


Instructions for its use include:

Dilute well with rapidly running IVF flush solution. After infusion is complete, give brisk bolus approx. 200 cc IVF to flush veins.

The basic substances used in IVF flushes are sodium thiosulfate 5 and sodium bicarbonate. Without the bicarbonate and thiosulfate buffers patients would quickly succumb to the chemo poisons.


Itís a picture right out of hell using mustard gas instead of something vastly safer.


Sodium bicarbonate, potassium chloride, and calcium
chloride are used to maintain pH and electrolytes
within normal values in intensive care units.


We are talking about serious medicine when we talk about sodium bicarbonate.


Earlier and more frequent use of sodium bicarbonate is associated with higher early resuscitability rates and with better long-term neurological outcomes in emergency units. Sodium bicarbonate is beneficial during CPR.6


We are also talking about an exceptionally safe medicine when we talk about bicarbonate. Chemotherapy drugs and corticoids reduce the bone marrow production of cells. In addition, these drugs damage the integrity of the skin tegument, and of the respiratory and gastrointestinal tracts, facilitating the penetration of microorganisms into the host.


Bicarbonate does none of this.


Sodium bicarbonate lessens the development of polycystic kidney
disease in rats. Chronic administration of 200 mM sodium bicarbonate
to rats inhibited cystic enlargement and prevented thesubsequent
development of interstitial inflammation, chronic fibrosis, and uremia.7


On the other hand cancer treatments, including the most commonly used chemotherapy agents as well as the newest biologic and targeted therapy drugs, can harm a patient's heart - sometimes fatally.


Cardiologists at The University of Texas found in their review of 29 anticancer agents that there is no class of cancer drug that is free of potential damage to the heart. It is the organ that seems to be most sensitive to toxic effects of anticancer agents.


Even the newest targeted therapies, designed to attack only cancer cells, can cause cardiotoxicity.8


Bicarbonate ions and water are two of
the most natural compounds on Earth.


We do not have to fear bicarbonate intake.


And in fact, people who live in areas of the world with high amounts of bicarbonate in their drinking waters have a striking decreased mortality rate and a decreased prevalence of disease.


Sodium bicarbonate, though often used as a medicine, is unlike pharmaceutical compounds. It is a natural non-toxic substance that does not require clinical trials for an assessment of toxicity. Spring waters contain bicarbonate ions which are coupled mainly with sodium, potassium, calcium or magnesium ions.


A deficiency of bicarbonate ions in the body contributes to a range of diseases and medical conditions.


Sodium bicarbonate acts as a powerful, natural and safe antifungal agent,9 which when combined with iodine, would probably cover the entire spectrum of microbial organisms. The efficacy of sodium bicarbonate against certain bacteria and fungi 10 has been documented. Its role as a disinfectant against viruses, however, is not generally known. Sodium bicarbonate at concentrations of 5% and above was found to be effective with 99.99% reduction viral titers on food contact surfaces within a contact time of 1 min.11


Throughout this book we will see reports of doctors using bicarbonate to defeat fungal infections. 12 But it was not until Dr. Simoncini came along though that the concept arose that what these doctors where unknowingly doing was cutting down the fungal fields of cancer.

Not only is it good for diaper rash it can also kick the teeth out of just about any cancer given a chance.





This logo of the Arm & Hammer baking soda is not a joke.


Sodium Bicarbonate is just as advertised, it comes into any job you use it for just like a muscleman wielding a hardened mallet. It's good that it is strong! This book is telling you to take him into your own home and use him to kick butt on your cancer.

Bicarbonate is a truly strong universal concentrated nutritional medicine that works effectively in many clinical situations that we would not normally think of.


For instance: The treatment of Interstitial Cystitis and Painful Bladder Syndrome depends on "rescue" instillations (or cocktails) of customized solutions that can be placed in the bladder and immediately help reduce pain and discomfort. If the anesthetic is alkalinized with a precise amount of sodium bicarbonate, it dramatically improves its ability to pass through the mucous to reach and soothe the irritated nerves and tissues beneath. 13

In reality we need a more descriptive image for bicarbonate. Its pharmacological characteristics, even though widely used, are not well understood. What does bicarbonate really do?


Well, instead of a muscleman with a mallet, an even better image would be a strong janitor mopping up the messes and carrying the poisons away. This strong janitor protects tissues and leaves an alkaline film or trail behind to make sure everything stays safe. In medicine, sodium bicarbonate is the cleaning and security man proven loyal through decades of faithful service.

Sodium bicarbonate is the last medicine in the world one needs to be afraid of.

Understand that this is perfectly legal. Just don't tell your doctor about it until after your cancer is gone. Better yet, tell him you have carefully studied chemo pharmacology and have decided that the most effective element in most protocols for cancer is the bicarbonate. Tell him that you have been doing it at home without his permission or authority while exercising your legal right to eat anything and everything sold in the supermarket for oral consumption.


That's right! You can just go to the supermarket and follow, in part, the instructions that are right on the box for maximum oral doses.


Sodium bicarbonate is only classified as a medicine if it is in injectable form. Otherwise it is a legal food item found in every supermarket useful for literally hundreds of applications. It is so useful, effective and safe that it will even help rid us of our cancers.

We can all be thankful that oncologists have been using bicarbonate. They have established it as a consistent part of their cancer treatment protocol. The embarrassment to them is that they did not know nor want to know about the real significance of bicarbonate. They do not understand their dependency on it and what it is really doing to their cancer patients.


It is like they had a chemical genius chained and enslaved in the basement. Meanwhile upstairs, while sitting at their desks, they pretend bicarbonate is nothing more interesting than a saline solution or water.


They end up giving all the credit to their poisonous treatments while hiding as much as possible the terrible toxicity and life threatening side effects.



The National Cancer Institute recommends that

sodium bicarbonate for treatment of Oral mucositis,

which is an inflammation of oral mucosa resulting from

chemotherapeutic agents or ionizing radiation. 14



There are no promises or guarantees about being cured just as there are no guarantees you will be alive tomorrow.


There are other factors beside biochemical ones that have a great deal of leverage over our health and our fate. One needs a will to live plus an openness that includes the ability to listen for ways to find the most appropriate form of cancer treatment.


Sodium bicarbonate is as safe as chicken soup and probably more effective than any other single element in any cancer protocol and it can be taken simply through oral administration making it a treatment for the masses as well as the elite who only want the best.

There are other basic substances like iodine, magnesium chloride and even THC (medical marijuana in oral form) which run neck and neck with bicarbonate's ability to confront cancerous tissues. And there are other substances that should be used also to heighten effectiveness of treatment. There are many natural medicinals that are of proven help to cancer patients.


THC, if legal, would cost little more than bicarbonate because it's a weed you can grow in your own backyard.


A month of heavy duty magnesium chloride treatments would not reach much above fifty dollars.

One also has to pay attention to the causes of cancer. One major cause is the high levels of mercury that come from dental amalgam and other sources like yearly flu vaccination shots, which mostly have mercury in them. God forbid you live anywhere downwind of a coal fired power station, a crematorium or even a municipal incinerator all of which put massive amounts of mercury into the air and nearby environments.


Chelation of mercury is an absolute necessity and it is best to find the most natural ways of doing that. But when all is said and done nothing is easier then to pull down a box of Arm and Hammer off the shelves and start taking it orally to defeat your cancer. Nothing could be simpler.

Taking bicarbonate does not prevent one from entertaining a full and complete cancer protocol.

There are many life saving cancer-busting substances like bicarbonate that are easily obtainable. One has to be crazy not to take more than several of them at the same time one is using the bicarbonate. There is no reason to take chances or play Russian Rolette with one's cancer or life. It is certain that sodium bicarbonate is a cancer treatment because it is used by oncologists and other personnel associated with the treatment of cancer victims.


But, as in anything, there are limits to the bicarbonate's power. It will not, for instance, overcome ones' magnesium, iodine and selenium deficiencies. A person still needs plenty of clean water and sun (vitamin D3). (See my 900 page book Winning the War on Cancer for a discussion of some of the issues including the Rising Tide of Mercury story and natural chelation methods. This work will also be presented in my upcoming book Natural Allopathic Medicine)

One of the most important things about magnesium chloride, iodine and bicarbonate is that they are not on Codex's list of controllable items.

Through all these years and multi-billion dollar cancer research projects we find out that it was probably the bicarbonate that has been saving cancer patients' lives. Certainly it saves some of the patients from oncology's madness in choosing deadly poisons.


The choice of the word madness here is quite literally for several studies have shown chemotherapy drugs to do damage to the brain. It is going to come as a great embarrassment to oncologists to learn that the most basic substance in their chemo protocol - sodium bicarbonate - is not only the safest but the most effective item in their hands.


It certainly will not give the patient "chemo brain," which can include:

  • suffering impaired concentration

  • memory loss

  • even vision problems

  • dementia

  • seizures



1 Okamura et al. 1985, Speroff et al. 1994.


3 SODIUM BICARBONATE 50mmol in each Liter of IV hydration fluid and/or SODIUM BICARBONATE 1000mg/m≤ PO q6h. Post-Chemotherapy Treatments: Serum Methotrexate levels- 30 minutes after infusion ends; q12h intervals from the start of the infusion x 2; then at 0800H daily for at least one day. For HYDRATION: Continue IV fluid at 100-125mL/hour, to maintain urine output >60mL/hr. Measure strict in and out q1h x 24 hrs. For ALKALINIZATION: Continue pre-chemo alkalinization for 24 hours after infusion ends.

4 Enhancement of chemotherapy by manipulation of tumour pH. Raghunand N, He X, van Sluis R, Mahoney B, Baggett B, Taylor CW, Paine-Murrieta G, Roe D, Bhujwalla ZM, Gillies RJ. Arizona Cancer Center.

5 This drug is HIGHLY TOXIC and both powder and solution must be handled and administered with care. Inhalation of dust or vapors and contact with skin or mucous membranes, especially those of the eyes, must be avoided. Due to the toxic properties of mechlorethamine (e. g., corrosivity, carcinogenicity, mutagenicity, teratogenicity), special handling procedures should be reviewed prior to handling and followed diligently. Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur. If leakage of drug is obvious, prompt infiltration of the area with sterile isotonic sodium thiosulfate (1/6 molar) and application of an ice compress for 6 to 12 hours may minimize the local reaction. For a 1/6 molar solution of sodium thiosulfate, use 4.14 g of sodium thiosulfate per 100 mL of Sterile Water for Injection or 2.64 g of anhydrous sodium thiosulfate per 100 mL or dilute 4 mL of Sodium Thiosulfate Injection (10%) with 6 mL of Sterile Water for Injection.

6 Resuscitation outcome in emergency medical systems with increased usage of sodium bicarbonate during cardiopulmonary resuscitation. Bar, Joseph G et al; Acta Anaesthesiol Scand. 2005 Jan;49(1):6 Entrez PubMed

7 Torres VE, Cowley BD, Branden MG, Yoshida I, Gattone VH. Nephrology Research Unit and Division of Nephrology, Mayo Clinic, Rochester, Minn 55905, USA. Exp Nephrol. 2001;9(3):171-80.

8 The study was funded by the Department of Cardiology at M. D. Anderson Cancer Center. Co-authors include Michael Ewer, M.D., Ann Tong, M.D., Daniel Lenihan, M.D., S. Wamique Yusuf, M.D., Joseph Swafford, M.D., Christopher Champion, M.D., Jean-Bernard Durand, M.D., Harry Gibbs, M.D., and Alireza Zafarmand, M.D.


9 There has been considerable interest in the use of baking soda (sodium bicarbonate, NaHC03) and potassium bicarbonate (KHC03) to control powdery mildew and other fungal diseases of plants. The use of baking soda as a fungicide is not a new idea. In Alfred C. Hottes' A Little Book of Climbing Plants, published in 1933 by the A.T. De La Mare Co. of New York, mention is made of using one ounce of baking soda per gallon of water to control powdery mildew (PM) on climbing roses. The author credits the idea to a Russian plant pathologist, A. de Yaczenski. In the August, 1985 issue of Organic Gardening magazine, a short article by Warren Shultz entitled "Recipe for Resistance" reports that researchers in Japan obtained effective control of PM on cucumbers, eggplants, and strawberries. They suggested weekly sprays of VA ounce baking soda per gallon of water. An article in the June, 1990 issue of Greenhouse Manager magazine summarizes the results of three years of testing baking soda as a fungicide for roses. Cornell University researcher Dr. R. Kenneth Horst observed suppression of PM and blackspotóboth major problems for New York rose growers. Roses were sprayed every 3 to 4 days with a water solution of baking soda and insecticidal soap.

10 Sodium Carbonate and Sodium bicarbonate were equal and superior to the other salts for control of green mold on oranges. Commun Agric Appl Biol Sci. 2007;72(4):773-7.

11 International Journal of Food Microbiology. Volume 109, Issues 1-2, 25 May 2006, Pages 160-163. Virucidal efficacy of sodium bicarbonate on a food contact surface against feline calicivirus, a norovirus surrogate Yashpal S. Malik and Sagar M. Goyal. Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota. The virucidal efficacy of sodium bicarbonate was enhanced when it was used in combination with aldehydes or hydrogen peroxide.

12 Prof. Bernard Paul said, "I have used the baking soda to stop the spread of the 'powdery mildew fungus' on the grapevine at a time when the disease was going out of control! It did not cure the grapevine but did stop the spread of the disease."