|

by A Midwestern Doctor
February 13, 2026
from
Mercola Website
PDF Version
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A Midwestern Doctor (AMD)
is a board-certified physician from the
Midwest and a longtime reader of Mercola.com.
I appreciate their
exceptional insight on a wide range of topics and I'm grateful to
share them.
I also respect AMD's desire to remain anonymous since
AMD is still on the front lines treating patients.
To find more of
AMD's work,
be sure to check out
The Forgotten Side of Medicine
on Substack.
|

Story at-a-glance
-
Despite decades of statin use costing approximately $25
billion annually in America alone, heart disease remains
the leading cause of death, suggesting the cholesterol
hypothesis that drives
statin prescriptions is
fundamentally flawed
-
Studies show that lowering cholesterol with statins does
not reduce heart disease, and yet these findings are
ignored while statin guidelines are created by experts
paid by pharmaceutical manufacturers
-
Malcolm Kendricks clotting model provides a superior
explanation for heart disease: atherosclerotic plaques
result from repeated damage to blood vessel linings
which the body repairs with layers of clots
-
The
medical establishment dismisses widespread reports of
statin injuries as "nocebo effects," paralleling how
COVID-19 vaccine injuries were dismissed as "anxiety,"
despite extensive evidence corroborating the injuries
-
The
actual causes of heart disease - fine particulate matter
from pollution and cigarettes, lead exposure, chronic
stress, and endothelial damage - receive minimal
research funding because effective interventions cannot
be patented and sold as expensive pharmaceuticals like statins
Frequently in science, fundamental facts are altered to create a
profitable industry.
Recently,
I showed how this occurs with blood pressure:
rather than
causing arterial damage, high blood pressure is a response to
arterial damage that ensures damaged arteries can still deliver
blood to the tissues.
In turn, rather than helping patients, aggressively lowering blood
pressure can be quite harmful.
In this article, I will look at the
other half of the coin,
statins, cholesterol, and heart disease - something that harms
so many Americans, it was poignantly discussed by Comedian Jimmy
Dore.
First, they scammed you on skin cancer
when the sun is good
for you.
Now, they're scamming you again on cholesterol
to sell you a
lifetime medication.
This entire narrative of cholesterol
being the villain in
heart disease was built on a lie.
What doctors fail to tell you is
pic.twitter.com/bhhkFBBDbb
A Midwestern Doctor (@MidwesternDoc)
September 11, 2024
Video also
HERE...
Cholesterol and Heart Disease
Frequently, when an industry harms many people, it will create a
scapegoat to deflect blame.
Once this happens, a variety of other
sectors will jump on the bandwagon and create an unshakable societal
dogma.
For example,
the health of a population (or if they are being
poisoned by environmental toxins) determines how easily an
infectious disease can sweep through a population and who is
susceptible to it, but reframing infectious diseases as a
"deficiency of vaccines" it both takes the (costly) onus off the
industries to clean up the society and simultaneously allows them to
get rich promoting the pharmaceutical products that "manage" each
epidemic and the even larger epidemic of chronic
diseases caused by
those vaccines (discussed in detail
here).
Note: The major decline in infectious illness
credited to vaccines was actually the result of improved public
sanitation; when the data are examined (e.g.,
for smallpox) those early vaccination campaigns made outcomes
worse, not better...
In the 1960s and 1970s, a debate emerged over the causes of heart
disease.
On one side,
John Yudkin effectively argued that the sugar
being added to our food by the processed food industry was the chief
culprit.1
On the other side,
Ancel Keys (who attacked Yudkin's work) argued
that it was due to saturated fat and cholesterol.2
Note: Leaders in the field of natural medicine
have made a strong case that this spike came from the mass adoption
of seed oils3
(which thanks to our unprecedented political climate is at last
being discussed on the mainstream news4).
Likewise, some attribute this increase to the advent of water
chlorination.5
Ancel Keys won, Yudkin's work was largely dismissed, and Keys became
nutritional dogma.
A large part of Key's victory was based on his
study of seven countries (Italy, Greece, Former Yugoslavia,
Netherlands, Finland, America, and Japan), which showed that as
saturated fat consumption increased, heart disease increased in a
linear fashion.
However, this result was simply a product of the countries Keys
chose (e.g., if Finland, Israel, the Netherlands, Germany,
Switzerland, France, and Sweden had been chosen, the opposite
correlation would have been found).
Fortunately, it's gradually become recognized that Keys did not
accurately report his data.
For example,
recently an unpublished
56-month randomized study of 9,423 adults living in state mental
hospitals or a nursing home (which made it possible to rigidly
control their diets) that Keys directed was unearthed.6
It found that replacing half of one's animal (saturated) fats with
seed oil (e.g., corn oil) lowered their cholesterol, but for every
30 points it dropped, their risk of death increased by 22% (which
roughly translates to each 1% drop in cholesterol raising the risk
of death by 1%).
Note: Another (unpublished) study from the
1970s (of 458 Australians), found that partially replacing dietary
saturated fat with seed oils increased the risk of dying by 17.6%.7
Likewise, recently, one of the most prestigious medical journals in
the world published internal sugar industry documents.8
They showed the sugar industry had used bribes to make scientists
place the blame for heart disease on fat so Yudkin's work would not
threaten the sugar industry.9
Remarkably, it is now generally accepted that Yudkin was right, but
nonetheless, our medical guidelines are still largely based on Key's
work.
Likewise, the need to lower cholesterol to prevent heart disease is
still a dogma within cardiology,10,11,12,13,14,15
despite things like this Lancet study16
(Total
cholesterol and risk of mortality in the oldest old)
which in 1986 showed:
"During 10 years of follow-up from Dec 1, 1986 to Oct 1,
1996, a total of 642 participants died. Each 1 mmol/L increase
in total cholesterol corresponded to a 15% decrease in mortality
(risk ratio 0-85 [95% Cl 0·79-0·91])."
Statins Marketing
Once a drug is identified that can "beneficially" change a number,
medical practice guidelines will inevitably shift to prioritizing
treating that number in more and more people.
For example,
this is what happened with blood pressure:

Prior to statins, it was difficult to reliably lower cholesterol,
but once they were introduced, research rapidly emerged arguing for
a greater and greater need to lower cholesterol (and put more people
on statins).

Note: In 2008 to 2009, 12% of Americans over 40
reported taking a statin, whereas in 2018 to 2019, that figure
increased to 35%,17
and Americans now spend approximately 25 billion annually on
statins.18
In tandem, a cancel culture (reminiscent of what we saw with
the COVID vaccines) has been created where anyone who challenges the use
of Statins is immediately labeled as a "statin denier" accused of
being a mass murderer, and effectively canceled.
Here, dissident
cardiologist Aseem Malhotra discusses the dirty parallels between
these two industries with Joe Rogan:
As such, beyond doctors being forced
to follow these guidelines, patients often are too
Ideological
doctors will retaliate against patients who do not take statins
(similar to how unvaccinated patients
were reprehensibly denied essential medical care during COVID-19),
employers sometimes require cholesterol numbers to meet a certain
threshold for employment, and life insurance policies often penalize
those with "unsafe" cholesterol numbers.
Statin Injuries
This status quo is inexcusable as
statins have a very high rate of
injury.
For example, the existing studies find between a 5% to 30%
rate of injuries,19
and Dr. Malhotra, having gone through all the existing evidence
estimates that 20% of statin users are injured by them.
Likewise, statins are well known for having a high percentage of
patients discontinue the drugs due to their side effects (e.g., one
large study found 44.7% of older adults discontinue the drugs within
a year of starting them,20
while another large study of adults of all ages found 47%
discontinued within a year).21
Statins in turn, are linked to a large number of complications that
have been well-characterized (e.g., mechanistically) and described
throughout the medical literature.22,23,24,25,26,27,28
One group of side effects are those perceived by the patient (which
often make them want to stop using the medications).
These include:
-
A high incidence of muscle pain29,30,31,32,33,34,35
-
Fatigue36,37
especially with exertion and exercise38
-
Muscle inflammation (whose cause
remains "unknown")39,40
-
Autoimmune muscle damage41,42,43,44
-
Psychiatric and neurologic issues
such as depression, confusion, aggression, and memory loss45,46,47,48,49,50,51,52,53
-
Severe irritability54
-
Sleep issues55
-
Musculoskeletal disorders and
injuries56,57
-
Sudden (sensorineural) hearing
loss58
-
Gastrointestinal distress59
The other group are those not overtly noticed by the patient. These
include:
-
Type 2 diabetes60,61,62,63,64
particularly in women65,66,67
-
Cancer68,69,70,71
-
Liver dysfunction and failure72,73
-
Cataracts74,75
-
ALS-like conditions and other
central motor disorders (e.g., Parkinson's disease and
cerebellar ataxia)76,77,78,79,80
-
Lupus-like syndrome81
-
Susceptibility to herpes zoster
(shingles)82,83,84
-
Interstitial cystitis85
-
Polymyalgia rheumatica86
-
Kidney injury87,88
-
Renal failure89
From the start, I noticed statin patients often reported numbness,
muscle pain, or cognitive issues after starting these drugs, which
resolved once they stopped.
When this was brought up with their
doctors, the response was often hostile, with doctors insisting statins couldn't be the cause, (citing their own experience of never
having seen this happen to a patient) or claiming the patient needed
to continue the medication regardless to avoid a heart attack.
In turn, as the years went by, I saw increasingly elaborate excuses
being created to protect the statins from an ever-increasing
awareness of their dangers.
A common one was the "nocebo effect"
- the idea that negative expectations caused the reported symptoms.
For example,
I lost count of how many doctors I knew who cited this
2016 study90
when patients stated they had been injured.
The nocebo effect is the opposite of the placebo effect.
While the
placebo effect occurs when a person experiences positive outcomes
from a treatment because they believe it will help, the nocebo
effect happens when negative outcomes arise simply because a person
expects harm from a treatment, even if the treatment itself is
harmless or ineffective.
This theory was used to dismiss patients' experiences despite the
fact that many were unaware of possible side effects until they
occurred and then looked them up.
If you take this story and replace "statin" with COVID-19 vaccines,
you will see it is essentially what everyone has experienced over
the last four years (e.g., I lost count of how many times vaccine
myocarditis was diagnosed as "anxiety").
Note: Two adverse event reporting systems exist
for adverse reactions to pharmaceuticals, MedWatch91
and FAERS.92
Like VAERS, they suffer from severe underreporting (it is estimated
only 1% to 10% of adverse events are reported to them), but
nonetheless, thousands of (ignored) reports can be found there of
the common injuries which result from statins.93
'Cholesterol' Plaques
Many medical beliefs emerge from
the pharmaceutical marketing
departments.
For example, the widespread belief that depression is
due to a "chemical imbalance"
is actually false and never had any evidence supporting it.
Likewise, they made us believe heart disease results from fat
clogging the arteries, much like it does for a drain pipe, as this
metaphor is easy for everyone to visualize and immediately elicits a
sense of disgust.

However, given that there is no link
between cholesterol and heart disease, is it necessarily true?
Malcolm Kendrick MD, in turn, discovered that the well-known risk
factors for heart disease do not corroborate the standard model.94
For example, to calculate the risk of heart disease, England
combines the adjustable risks for heart disease (e.g., age) with the
conditions commonly associated with causing heart disease.95

Likewise, in a 2017 study, the records
of 378,256 English patients were analyzed by an AI system to
identify which characteristics were associated with the highest risk
of a cardiovascular event over the next 10 years.
The ten greatest
risk factors (in order) were:96

From this, Kendrick concluded that the common thread was that many
of these (e.g., lupus or cortisol) are associated with damage to
blood vessels and impaired microcirculation (a consequence of such
damage) rather than with cholesterol.97
Presently,
cardiology believes cholesterol somehow gets into a blood
vessel and then damages it (leaving an atherosclerotic plaque).
Kendrick saw that a forgotten model (that the medical profession
largely buried) provides a much better explanation of the causes of
heart disease:
-
Blood vessels get damaged.
-
The body repairs the damage with
cholesterol containing clots.
-
As clots heal, they are pulled
inside the blood vessel wall, and a new layer of endothelium
(blood vessel lining) grows over them.
-
As this occurs multiple times in
the same area, the damage (plaques) under the blood vessel
becomes more abnormal.

Some of the key points of evidence he uses to support this argument
are:98
-
Most of the risk factors for heart
disease overlap with things that would be expected to damage the
blood vessel lining (endothelium).
-
Plaques tend to form at arterial
branch (junction) points, which are the parts of the artery that
are subjected to the greatest shear stress.99
-
When you examine the components of
a plaque, they are found to contain the same debris found in
blood clots.100,101,102
-
There is no established mechanism
for how cholesterol from the bloodstream can get under the
endothelium. However, red blood cells (which play a key role in
forming clots103)
contain a large amount of cholesterol (50% of the total amount
in the bloodstream104),
and hence will bring it into clots that form.
-
Plaques contain cholesterol
crystals. These crystals can form only from free cholesterol,105
which is present in red blood cells, but not from the "bad"
cholesterol that circulates in the bloodstream (contained within
lipoproteins). Likewise, much of the cholesterol found in
atherosclerotic plaques is free cholesterol.106
-
The remnants of lipoproteins that
are found in plaques are not cholesterol lipoproteins, but
rather lipoprotein A, something the body uses to repair damage
to the arterial walls.107
This is supported by the fact elevated blood lipoprotein A
levels are associated with increased lipoprotein remnants in
plaques108
and that the specific marker of lipoprotein A is found to
concentrate in atherosclerotic plaques.109
Lipoprotein A in turn is problematic because,
while it can patch
and repair arterial damage, it also makes clots resistant to
subsequent degradation, guaranteeing that they will eventually
be pulled under the endothelium and transformed into an
atherosclerotic plaque (which may in turn explain why elevated
lipoprotein A levels are associated with a three-fold increase
in the risk of a heart attack or stroke110).
In short,
a strong case can be made that our entire heart disease
model rests on a variety of correlations that were erroneously
assumed to demonstrate causation.
Sadly, while the "correlation is
not causation" mantra is frequently used to dismiss anything that
challenges the orthodoxy, you will frequently find overtly false
correlations that support the medical industry's bottom line being
treated as unquestionable dogmas.
Note: One of the best examples is the
widespread belief vaccines eliminated infectious disease, even
though no correlation exists (whereas
public sanitation directly correlates with the elimination of
infectious diseases).

The Causes and Treatments of Heart Disease
Kendrick's model essentially argues the following:
-
Most cardiovascular disease
results from the blood vessel lining becoming damaged (due to
the atherosclerotic lesions) and losing the ability to perform
the normal functions (e.g., nitric oxide secretion) that allow
it to protect the circulation.
-
Inflammation and periods of
prolonged and severe stress (e.g., from mental illness,
cigarettes, or extreme social oppression) frequently damage the
endothelium and hence contribute to heart disease.
-
Heart attacks are due to blood
clots (which frequently are a result of damaged endothelium)
interrupting a critical blood supply to the heart.
Remarkably, most of Kendrick's model is in complete agreement with
the conventional cardiovascular disease paradigm, he just emphasizes
stress and inflammation rather than cholesterol and prioritizes
treating the functional impairments of the blood vessels (e.g.,
reduced nitric oxide synthesis).
Note: Kendrick argues the small benefits
experienced from statins are likely due to the drugs also having
anti-inflammatory effects111
and increasing endothelial nitric oxide.112
Similarly, smoking is well recognized to cause heart disease because
it damages the blood vessels (e.g., by creating plaques and
impairing their ability to make nitric oxide113),
but we rarely ask why or note that similar damage has been
repeatedly demonstrated with,
-
fine particulates from coal mines114
-
breathing air in crowded cities115
-
cooking with a wood burning stove116
-
being exposed to wildfire smoke117
Likewise, lead is quite damaging to the endothelium,118,119
rapidly enters the bloodstream once inhaled,120
and a strong correlation exists between lead use in gasoline and
heart disease in America.121
Note: It's estimated that around 400,000 deaths
each year in America are due to lead exposure122
and in a study of 868 men, it was observed that high levels of lead
exposure (assessed by its presence in the bones) increased their
risk of dying by over 700%,123
particularly since lead returns to the bloodstream
as aging bones break down.
Sadly, as you cannot sell drugs for any of these causes of heart
disease, they rarely get mentioned, and instead almost all of the
research and discussions on heart disease are directed at
cholesterol.
Conclusion
Kendrick presciently argued that because of how much money has been
invested in establishing the cholesterol hypothesis, the industry
will never let it go.
This, in short, accounts for why we continue
to spend billions each on these drugs despite their benefit being
almost nonexistent (e.g., unbiased research shows taking statins for
five years, on average, only extends life by 3 to 4 days124
- and only in men)125
and their harms being common and immense.
Fortunately, we have at last reached a point where real progress is
being made.
For example, despite immense institutional pushback, MAHA recently updated the Federal Dietary Guidelines to at last
correct the 50-year-mistake created by Key's doctored data and
acknowledge the importance of consuming healthy animal fats.

The insatiable greed which birthed the unconscionable COVID vaccines
and their mandates has at last opened the public's eyes to the
marketing myths
the pharmaceutical industry has bombarded us from
birth with so we perpetually consume their products.
Because of
that, we at last have a once in a lifetime opportunity to correct
many of these disastrous policies, and as
MAHA's recent revision of
the food pyramid shows (which I never imagined would occur), change
is actually happening.
Unfortunately, decades of other disastrous health policies also need
to be fixed, and for that to happen, it is essential we bring
awareness to each of them.
I sincerely thank each of you for
allowing me to share the truth about statins with you; so many
people I know have been hurt by them, and with your help, we can at
last end this.
Author's Note: This is an abridged version of
a longer article about the great cholesterol scam which goes
into greater detail on the dangers of statins, the actual causes of
heart disease, and the natural ways to safely heal the arterial
system and prevent heart disease. That article and its additional
references can be read
here.
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