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			by Sayer Ji 
			
			originally October 03, 
			2017 
			updated March 09, 2019 
			from 
			GreenMedInfo Website 
			
			  
			
			  
			
			  
			
			  
			
			  
			
			  
			
			  
			
			
			 
			There is much more than meets the eye with the banana.  
			
			  
			
			A household 
			favorite, a lost-leader at the grocery store, a metaphor for 
			psychiatric problems, a mainstay of comic slap stick, the banana has 
			woven itself deeply into human affairs, on both gut and mental 
			levels.  
			
			  
			
			And this relationship is at least 10,000 years old, as far 
			as conscious human cultivation of the species goes. 
			 
			But, many do not realize that the banana is more than just an 
			exceptionally starch-rich fruit, but has a complex biochemistry, 
			with unique pharmacologically active properties which scientists 
			have characterized. 
			 
			Bananas actually contain the catecholamines dopamine [i] and norepinephrine,
			[ii] the very same adrenal hormones released in the 
			human body when it undergoes the typical "fight-or-flight" response. 
			 
			
			  
			
			It is believed that the banana plant uses the biosynthetic pathway 
			for catecholamines when under the stress of attack to fight off 
			infectious pathogens such as in crown rot disease. [iii]  
			
			  
			
			Some 
			varieties excrete a form of serotonin in their sap, [iv] and there 
			is even mention in the biomedical literature of the discovery of the NSAID drug 
			naproxen (trade name 
			
			Aleve) within the banana cultivar
			
			Musa acuminate. 
			 
			Sound crazy...?  
			
			  
			
			Well, that's to be expected from a fruit we commonly 
			associate with a state of unbridled madness. 
			 
			But the banana has a secret second life. It has been observed slyly 
			practicing medicine without a license, and indeed, seems readily 
			equipped with the following nutritional "super powers"... 
			
			  
			
			  
			
				
				Green Banana Is Anti-Diarrhea 
				 Before a banana is ripened, while it is in its green state, it 
			contains starches which are resistant to digestion, but have been 
			studied in combination with pectin to significantly reduce 
			intestinal permeability and fluid loss in those suffering with bouts 
			of diarrhea. [v] [vi]  
				
				  
				
				Even when used without pectin, green banana has 
			been found to hasten recovery of acute and prolonged childhood 
			diarrhea when managed at home in rural Bangladesh. [vii] 
				  
				
				 
				Banana Is Anti-Ulcer Activity 
				 Banana powder has been studied to prevent ulcer formation induced by 
			a variety of drugs, including, 
				
					
						- 
						
						aspirin 
						 
						- 
						
						indomethacin 
						 
						- 
						
						phenylbutazone 
						 
						- 
						
						prednisolone 
						 
						- 
						
						cysteamine 
						 
						- 
						
						histamine 
						 
					 
				 
				
				Researchers have found that 
			banana powder treatment not only strengthens mucosal resistance 
			against ulcerogens but also promotes healing by inducing cellular 
			proliferation. [viii]  
				
				  
				
				One of the anti-ulcer compounds identified 
			within unripe banana is the flavonoid known as 
				
				leucocyanidin, and 
			which is particularly effective against aspirin-induced erosion.
				[ix] 
				  
				
				 
				Banana Peel Suppresses Prostate Gland Growth 
				 Banana peel has been found to suppress testosterone-induced prostate 
			gland enlargement. [x] 
				  
				
				 
				Banana Stem Extract suppresses Oxalate Kidney Stones 
				 A water extract of banana stem extract has been found to suppress 
			the formation of oxalate-associated kidney stones in the animal 
			model, leading researchers to conclude that it "may be a useful 
			agent in the treatment of patients with hyperoxaluric 
			urolithiasis." [xi] 
				  
				
				 
				Banana Consumption Protects the Skin Against UV-Light Damage 
				 UV-B light induced skin damage may be prevented or reduced through 
			the consumption of bananas, with a protective effect against loss of 
			skin elasticity. [xii] 
			 
			
				
				 
				Banana Has Anti-Diabetic Properties 
				
  Banana flower extract has been studied in a type 1 diabetic 
			model, [xiii] and has been found to have both antioxidant and blood 
			sugar lowering effects.  
				
				  
				
				Banana root extracts have been discovered to 
			contain blood sugar lowering properties comparable in efficacy to 
			the drug glibenclamide (trade name Glyburide). [xiv]  
				
				  
				
				Also, unripe 
			banana contain starches resistant to hydrolysis and therefore 
			beneficial to diabetics. [xv] 
				  
				
				 
				Banana Contains a Variety of Anti-Infective Compounds 
				 Banana contains compounds with demonstrable, 
				
					
						- 
						
						anti-MRSA 
						activity [xvi]   
						- 
						
						anti-HIV replicative 
						activity [xvii] [xviii] 
						  
						- 
						
						following metabolic 
			transformation by fungi, anti-leishmanicidal activity [xix] 
						 
					 
				 
				
				The 
			leaves of the plant are used in many centers in India during the 
			care of patients with toxic epidermal necrolysis (TEN) and other 
			extensive blistering disorders which can result in deadly sepsis in 
			the absence of treatment. [xx] 
			 
			
			  
			
			  
			
			  
			
			Final Remarks 
			
			 
			Whatever you do, don't slip up and buy non-organic bananas. Like 
			other foods that are grown in massive monocultures, without crop 
			rotation, they are a pesticide-intensive crop.  
			
			  
			
			And this concern 
			extends beyond simply what agrochemicals you are exposing your body 
			to.  
			
			  
			
			In conventional farming, the planet gets carpet-bombed as well 
			with these nasty toxicants, and since we all live on the same Earth, 
			eventually those pesticides make it back up the food chain to you, 
			whether you choose to eat organic or not. 
			 
			 
  
			
			  
			
			
			References 
			
				
					- 
					
					K Kanazawa, 
					H Sakakibara. High content of dopamine, a strong 
					antioxidant, in Cavendish banana. J Agric Food Chem. 
					2000 Mar ;48(3):844-8. PMID: 
					
					10725161  
					- 
					
					J M FOY, J 
					R PARRATT. A note on the presence of noradrenaline and 
					5-hydroxytryptamine in plantain (Musa sapientum, var. 
					paradisiaca). J Pharm Pharmacol. 1960 Jun 
					;12:360-4. PMID: 
					
					13824274  
					- 
					
					L Lassois, 
					C De Clerck, P Frettinger, L De Lapeyre De Bellaire, P 
					Lepoivre, M Haïssam Jijakli. Catecholamine biosynthesis 
					pathway potentially involved in banana defense mechanisms to 
					crown rot disease. Commun Agric Appl Biol Sci. 2011 
					;76(4):591-601. PMID: 
					
					22702179  
					- 
					
					Pongsagon 
					Pothavorn, Kasipong Kitdamrongsont, Sasivimon Swangpol, 
					Siripope Wongniam, Kanokporn Atawongsa, Jisnuson Savasti, 
					Jamorn Somana. Sap phytochemical compositions of some 
					bananas in Thailand. J Agric Food Chem. 2010 Aug 11 
					;58(15):8782-7. PMID: 
					
					20681667  
					- 
					
					G H Rabbani, 
					Telahun Teka, Shyamal Kumar Saha, Badiuz Zaman, Naseha Majid, 
					Makhduma Khatun, Mohammad A Wahed, George J Fuchs.
					
					
					Green banana and pectin improve small intestinal 
					permeability and reduce fluid loss in Bangladeshi children 
					with persistent diarrhea. Dig Dis Sci. 
					2004 Mar;49(3):475-84. PMID: 15139502  
					- 
					
					G H Rabbani, 
					T Teka, B Zaman, N Majid, M Khatun, G J Fuchs.
					
					
					Clinical studies in persistent diarrhea: dietary management 
					with green banana or pectin in Bangladeshi children.
					Gastroenterology. 2001 Sep;121(3):554-60. PMID: 
					11522739  
					- 
					
					G H Rabbani, 
					C P Larson, R Islam, U R Saha, A Kabir.
					
					
					Green banana-supplemented diet in the home management of 
					acute and prolonged diarrhoea in children: a community-based 
					trial in rural Bangladesh. Trop Med Int 
					Health. 2010 Oct;15(10):1132-9. PMID: 20831671  
					- 
					
					R K Goel, S 
					Gupta, R Shankar, A K Sanyal.
					
					
					Anti-ulcerogenic effect of banana powder (Musa sapientum 
					var. paradisiaca) and its effect on mucosal resistance.
					J Ethnopharmacol. 1986 Oct;18(1):33-44. PMID: 
					3821133  
					- 
					
					D A Lewis, 
					W N Fields, G P Shaw. 
					
					A natural flavonoid present in unripe plantain banana pulp 
					(Musa sapientum L. var. paradisiaca) protects the gastric 
					mucosa from aspirin-induced erosions. J 
					Ethnopharmacol. 1999 Jun;65(3):283-8. PMID: 10404428  
					- 
					
					 Kiichiro 
					Akamine, Tomoyuki Koyama, Kazunaga Yazawa . Banana peel 
					extract suppressed prostate gland enlargement in 
					testosterone-treated mice. Dermatol Surg. 2005 
					Jul;31(7 Pt 2):855-60; discussion 860. PMID: 
					
					19734683  
					- 
					
					P K 
					Poonguzhali, H Chegu. The influence of banana stem extract 
					on urinary risk factors for stones in normal and 
					hyperoxaluric rats. Br J Urol. 1994 Jul 
					;74(1):23-5. PMID: 
					
					8044524  
					- 
					
					Jarupa 
					Viyoch, Khuanrudee Mahingsa, Kornkanok Ingkaninan. Effects 
					of Thai Musa species on prevention of UVB-induced skin 
					damage in mice. Food Chem Toxicol. 2012 Sep 8 
					;50(12):4292-4301. Epub 2012 Sep 8. PMID: 
					
					22986089  
					- 
					
					S P 
					Dhanabal, M Sureshkumar, M Ramanathan, B Suresh. 
					Hypoglycemic effect of ethanolic extract of Musa sapientum 
					on alloxan induced diabetes mellitus in rats and its 
					relation with antioxidant potential. J Nutr. 2010 
					Aug;140(8):1462-8. Epub 2010 Jun 16. PMID: 
					
					16260406  
					- 
					
					E O Adewoye, 
					V O Taiwo, F A Olayioye. Anti-oxidant and anti-hyperglycemic 
					activities of musa sapientum root extracts in alloxan-induced 
					diabetic rats. J Med Chem. 2010 Oct 
					28;53(20):7365-76. PMID: 
					
					20175413  
					- 
					
					J Thakorlal, 
					C O Perera, B Smith, L Englberger, A Lorens . Resistant 
					starch in Micronesian banana cultivars offers health 
					benefits. Pac Health Dialog. 2010 Apr;16(1):49-59. 
					PMID: 
					
					20968236  
					- 
					
					Qian Zhang, 
					Wenyi Kang. [Active compounds from rhizomes of Musa basjoo].
					Zhongguo Zhong Yao Za Zhi. 2010 Sep;35(18):2424-7. 
					PMID: 
					
					21141492  
					- 
					
					Allen H K 
					Cheung, Jack H Wong, T B Ng. Musa acuminata (Del Monte 
					banana) lectin is a fructose-binding lectin with 
					cytokine-inducing activity. Phytomedicine. 2009 
					Jun;16(6-7):594-600. Epub 2009 Feb 4. PMID: 
					
					19195858  
					- 
					
					Michael D 
					Swanson, Harry C Winter, Irwin J Goldstein, David M 
					Markovitz. A lectin isolated from bananas is a potent 
					inhibitor of HIV replication. J Biol Chem. 2010 Mar 
					19;285(12):8646-55. Epub 2010 Jan 15. PMID: 
					
					20080975  
					- 
					
					Juan Román 
					Luque-Ortega, Silvia Martínez, José María Saugar, Laura R 
					Izquierdo, Teresa Abad, Javier G Luis, José Piñero, Basilio 
					Valladares, Luis Rivas. Fungus-elicited metabolites from 
					plants as an enriched source for new leishmanicidal agents: 
					antifungal phenyl-phenalenone phytoalexins from the banana 
					plant (Musa acuminata) target mitochondria of Leishmania 
					donovani promastigotes. Antimicrob Agents Chemother. 
					2004 May;48(5):1534-40. PMID: 
					
					15105102  
					- 
					
					C R 
					Srinivas, V Shanmuga Sundaram, B Appala Raju, S Karthick 
					Prabhu, M Thirumurthy, A C Bhaskar. Achieving asepsis of 
					banana leaves for the management of toxic epidermal 
					necrolysis. Indian J Dermatol Venereol Leprol. 2006 
					May-Jun;72(3):201-2. PMID: 
					
					16766833  
				 
			 
			
			
			  
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