by Jesús Pérez
received by Email through A.K.
on January 29, 2009
Dear Sirs and Madams,
I take the liberty of attaching the theory I have
created, building on 20 years of empirical research on
the possible causes of viral and bacterial infections.
To express the results of my experience in a nutshell: I
have come to the conclusion that acid-basic balance in
our cells is at the root of a state of health or of
illness of a human being.
As I do not have the
resources or the background to follow up my ideas
scientifically, my aim in contacting the Foundation is
to ask for an opportunity to be taken seriously by the
scientific community, and for contacts with researchers
that might look into the notions expressed in the
attached outline. I am not asking the Foundation for
money but only help to be able to expose some ideas that
in many ways are contrary to current medical practice.
Health or illness might depend on the outcome of a struggle between
active substances (enzymes) against substrates of low solubility or
insoluble (inhibitory agents) in a blood circuit with acid-basic
balance (neutral pH). In other words, they depend on the struggle
between slightly alkaline native proteins against denatured acid
I have spent part of my life studying the origin of AIDS, Cancer and
other illnesses and I have come to the conclusion that at the root
of these diseases are the manipulation of foodstuffs and unbalanced
diets which produce acidosis, which in turn blocks oxidation,
combustion and excretion in the cells.
The inhibition and de-inhibition which takes place continually in
the human body alters the dynamic balance in the function of the
cells to manage a perfect colloidal dispersion of its molecules, and
this causes the development of diseases.
Drawing on my experience, I would like to demonstrate to what degree
our diet influences our state of health.
Endogenous viruses are denatured proteins
The origin of endogenous viruses is the following: we humans,
through our intake of food, introduce into our bodies denatured
proteins, which we should consider exogenous. Ribosomes are in
charge of synthesizing these exogenous proteins, causing mutations,
which are structural changes that transform them into endogenous
proteins. When recurrent mitochondrial mistakes occur they can turn
into viral proteins, such as HIV.
Viruses are ARN or ADN nucleic acid particles united to proteins. In
the synthesis of new proteins more personal phenomena intervene
within the body, as due to hereditary mechanisms or those derived
from the specific biochemical setup of an individual only those
proteins are synthesized that are specific to each human being.
Hereditary genes have the clue to the fact that they are
The unique composition of the proteins in all organisms allows them
to distinguish, and also to fight against all strange, denatured,
This is the basis of all mechanisms of
immunological defense, and for this reason it is logical to think
that the HIV virus is endogenous and not exogenous. This is to say,
the endogenous virus is created from a denatured protein because the
protein causes mitochondrial errors that give rise to successive
mutations of the protein synthesized by the ribosomes, converting it
into a viral protein.
At present, new theories are being formulated, but no solutions are
found for AIDS. In spite of the alarming reports from the WHO, where
serious contradictions are found within the very same scientific
community, and in spite of the sterility of its results, scientists
deny that the therapies imposed today are a serious error, as they
are all geared towards keeping the AIDS virus to penetrate the cell.
Medical scientists believe that infectious diseases are caused by
viruses or bacteria that accidentally penetrate the human body,
mutating, multiplying, and also being transmitted by contagion from
one person to another.
These researchers, in order to prevent and fight against such
diseases, have been looking for methods of immobilizing enzymes
(directed mutagenesis), vaccines, antibiotics, inhibitors, denatures
substances, etc. giving rise to chemical warfare against the
different micro-organisms that inhabit our body.
A NEW THEORY
ABOUT AIDS (IMMUNITARY OVERLOAD)
Medical science today is extremely demanding and it does not accept
as valid any new theories, even if they might look promising, if
they have not been tested and confirmed by different groups of
For medical scientists, to claim that the HIV virus is endogenous is
tantamount to being heretical, because, according to the same
source, it has been proven that it is exogenous, even if nobody has
been capable of demonstrating what its origin is.
The erroneous belief that viruses cause the disease and that they
should be controlled or eliminated is widespread, just as the
narrowness of mind of those to whom any other idea that might appear
in relation to this topic, such as the one that the badly nourished
cell causes the disease and as a consequence transforms exogenous
protein into endogenous viral protein, thus developing an infection.
This is to say, first the cells become
diseased and then the virus appears. For this reason, the virus is
not the cause of the infection. This same procedure applies in the
cancer of the uterus.
The papilloma virus (HPV) has no direct relationship
with the cancer and it is not the cause of cancer of the uterus.
Vaccinating against HPV is not just medically useless, it is also
harmful to the health of adolescents and young women. Scientists do
not know why viruses are reactivated and cause permanent infections.
Actually, no-one has, as yet, found the way to kill any virus.
Luc Montagnier, Head Researcher on Viral Oncology at the
Pasteur Institute, has publicly said that his scientific
“is to demonstrate that there is
something more than HIV in the cause of the disease”.
According to a declaration by the French
scientist during his contribution to the IX International
Conference on AIDS in Berlin,
“HIV is not the only responsible for
the syndrome, and it even does not attack nor destroy the cell
of the immune system. It can happen that, at a certain moment,
not even HIV plays any role at all. Only the joint action of one
or several co-factors can explain the process of cellular
apoptosis that brings about the destruction of a great number of
Kary Mullis, winner of the
Nobel Chemistry Prize, at a congress in Toledo (Spain) in April
1994, denied that HIV is the cause of AIDS:
“I don't know how to explain this in
a few words, but I have dates that confirm that AIDS is not an
infectious disease, it is not caused by the virus”, the
Inhibitory action: If
non-natural substrates that reduce the enzyme's activities
are added to an enzymatic system, this system is said to
have been inhibited, and the substrate thus used is called
Many inhibitors are agents that denature the enzymes, as the
latter are protein molecules and they are sensitive to many
agents, especially chemical ones. These agents that inhibit
enzymatic activity act on practically all enzymes, which
shows that their action is not specific, but that they act
on all protein molecules. If there is a large amount of
natural substrate, the inhibitor is dominated and displaced,
and the natural substrate enters the active areas of the
enzyme to allow the catalytic activity to recommence.
None of the viruses that affect humankind have been found to
have a viral origin, because the viruses live and develop
within our organism and become manifest only when they have
been induced through the presence of denatured substances to
a mutation of its own microorganisms.
Spontaneous mutations: They are
the result of normal cell activity, or of its interactions
with its natural medium. Most of them are caused by errors
in the replication process, or in the process of ADN repair
or re-combination. (In short, they would be those mutations
that are not caused experimentally).
Induced mutations: They are
those caused by previous experimental alteration of ADN,
directly or indirectly, through physical or chemical agents
Suppressing mutation: is the
mutation that reduces the performance of the mitochondria,
due to the fact that, apart from its suppressing capacity,
it induces errors in normal mitochondrial RNA readings.
Mutations are specific genetic defects,
that is, molecular alterations of genetic material. Such mutations
cause alterations in enzymes and other proteins.
How many protein mutations are necessary for them to become viral
In order to know when such mutations or changes are carried out it
is necessary to find out which are the denatured substances that
produce such transformations, and it is obvious that nutrition
malpractice should be partly to blame. Nutrition is involved in the
change of the molecular structure of our microorganisms causing them
This action of transformation of the
microorganism into HIV virus can only take place in those specific
cells that are genetically predisposed. The substrates produced
contribute to a depression of spinal marrow, affecting the
quantitative and qualitative production of lymphocytes. This is the
reason why the origin of AIDS can be explained simply in terms of
“immunitary overload", i.e. a progressive self-poisoning of the
If, as seems to be the case, the so-called degenerating diseases
are really mitochondrial diseases insolubly bound to the
processes of "general debilitation" which opens the door to many
other diseases, it would be adequate to consider them the most
radical of all diseases, "the mother of all diseases".
It is an attack on our genetic material
due to acid-alkali imbalance.
AIDS IS A
The diseases caused by damage to the mitochondrial genome have in
common that they are produced by a deficiency in the ATP
biosynthesis, due to the fact that all the information contained in
this DNA is directed towards synthesis of proteins contained in the
Oxphos system. Such diseases appear in different forms and can
affect all our organs and tissues, as ATP synthesis takes place in
all of them. They can appear with certain clinical, morphological
and biochemical aspects that give rise to syndromes.
Mitochondrial malfunction can also
contribute to the syndrome of immunodeficiency.
The mitochondria deteriorate as a consequence of an accumulation of
mutations. When the mutated DNA passes a threshold it will show a
pathogenic phenotype, i.e. if PAT production falls below the
necessary minimum for the performance of the tissues, due to a
defect in the proteins encoded in mitochondrial DNA, an illness will
Mitochondrial toxicity is a kind of damage that will decrease the
number of mitochondria. If there are very few mitochondria in the
cell, it will stop working adequately, or it will not function at
all. The mitochondria deteriorate as time passes as a consequence of
an accumulation of mutations.
In October 1993, a research group in Kenya and Canada published the
results of an experiment consisting in maintaining 424 prostitutes
in Nairobi under observation for 10 years. In spite of having
carried out some 500 sexual encounters with HIV positive men, they
had not been infected by the virus. This study, published in the
journal Lancet, suggests that the prostitutes had a natural immunity
against the HIV virus.
Two years later a group of British physicians published their
research in the journal Nature Medicine.
They had found, in a group of Gambian
prostitutes, “a strange immunity against the AIDS virus”. The
researchers found that the women had –T cells, which kill those
cells that have been infected by the virus. The Institute of
Molecular Medicine at Oxford explained that the high level of
lymphocytes –T was the reason for their immunity.
Currently I ignore whether the study was followed up or whether both
projects have been abandoned, and if the prostitutes still have not
been infected by the HIV virus. In my opinion, the result of this
research throws doubt on the notion that HIV is contagious, and
leads me to believe that it is developed within those people who are
genetically predisposed, as a consequence of sustained imbalance in
their diet (i.e. that it is endogenous).
There are HIV positive patients who through the protease inhibition
treatment have developed diabetes, that is, first they have been HIV
infected and then they have become diabetic but,
IS THERE ANY
DIABETIC WHO, WITHOUT HAVING BEEN TREATED WITH ANTI-RETROVIRALS
HAS COME TO DEVELOP HIV?
and, if there is
not, SHOULD WE BELIEVE THAT INSULIN HAS THE PROPERTY OF
This would confirm that there is no
diabetic who has contracted HIV.
DEVELOPMENT OF HIV VIRUS
The amino acids are the basic elements of growth of all live beings.
When a human, or a HIV, cell multiplies, the genetic code is “read”.
Amino acids are created according to the genetic code and join
together in proteins in order to create the new cell, or new virus.
If a constant inhibitory diet has caused progressive changes in the
delicate biological balance of the human being, micro-organisms have
developed in the body, acting like endogenous mutagenic agents.
Researchers at the University of North Carolina and the
Department of Agriculture in the United States have established,
for the first time, a relationship between deficiencies in nutrition
and the development of dangerous viral mutations.
The results of this research were
published in the journal Nature Medicine.
“Through further experiments, the
American research group wishes to find out whether dietary
problems are a factor in the development of illnesses such as
the flu, hepatitis, meningitis, and other diseases that affect
Bad dietary habits gave rise, initially,
to the appearance of an incomplete virus, which, as it was not
detected by analyses, was supposed to be hidden in lymphatic
This is not really so, because as the
same type of diet was continued the constituent material is the
same, but the structural substrates which are a result of new
protein synthesis will continue creating, developing and completing
The genetic variants created new viruses of different molecular
structure, that is, endogenous viruses of new design, introduced
through chemical reactions of the substrate provided by bad dietary
habits. They accepted in their bases new molecular atoms, changing
their structure, and giving rise to the development of new viruses
that were more resistant to new structural rupture, staying inside
our body for the rest of our lives.
The cure of AIDS depends on whether the lymphocyte cells perform in
their optimum pH.
It is a source of preoccupation that the medical profession refuses
to accept this theory, or at least to take it seriously, even though
it has not been capable of demonstrating the origin of AIDS
Enzymes typically present a maximum of catalytic activity at a
specific pH. This value is called optimum pH.
Because enzymes are proteins, any sudden change in pH can alter the
ionic character of amino and carboxyl groups in the protein surface,
thus affecting the catalytic properties of an enzyme. If the pH is
high or low denaturing of the enzyme can follow, and consequently is
In December 1995, the use of the first inhibitor of HIV viral
protease was approved. Other inhibitor followed, and in mid-1996 a
new generation of inhibitors of viral inverse transcriptase,
intended to inhibit enzymatic functions, appeared on the market. I
believe it is a serious error to try to invert enzymatic functions
established by the very nature of a living organism.
That is, to keep the active principles
(enzymes) from carrying out their proper mission, which is
activation, as they are the protein catalysts that regulate the
speed with which physiological processes take place. As a
consequence, the deficiencies in enzymatic function cause
pathologies, secondary effects, and collateral damage through the
action of inhibitors that have drastic physiological consequences
due to the impairment of enzymatic activity, even if in only one
The enzymes protease and inverse transcriptase are very sensitive to
pH change and deviation, even if only few decimal points above or
below the optimum pH. Such changes can affect their activity
drastically and even small changes can cause denaturing of the
protein. Balanced “live” foodstuffs contribute to maintaining
intracellular pH stable (they are physiological dampers).
In the view of medical researchers, if the inhibitors of protease
and transcriptase are not effective, the enzymes will be activated
and the inhibition will not be concluded, the substrate is not
maintained within the cell to block it and the enzymes will be able
to “read” the viral genetic code and give rise to the new substrate,
which would be the “Troyan horse” of the infection.
If the inhibitors manage to block defending cells, on the one hand,
their function is also blocked, debilitating the immune system, and,
on the other hand, we have to ask ourselves: What is to be done with
the accumulated and multiplied viruses in order for them not be
absorbed by the inactive cells? And, if they multiply, which they
are bound to do: Which is the providing source? The blocked cells
cannot replicate new viruses.
Medical scientists, in this case, drastically separate from the
bases set by scientists experts in pH performance and enzymology,
and do not take into account that the effect of the co-factors in
enzymatic activity are given by the substances provided in the diet.
They do not take into account that the
influence the diet can have on the amount of inhibitors, nor on the
role physical activity, increase of temperature and change of pH,
which will make them lose effectiveness and give rise to new and
more resistant mutations. Native proteins can provide the essential
amino acids to the protease and transcriptase and de-block them.
When the sperm fertilizes the ovum, its mitochondria remain outside
the ovum, the fertilized zygote inherits only the mother’s
mitochondria. This inheritance from the mother crates a family tree
that will not be affected by the re-combinations of genes that take
place between the father and the mother. For this reason, Magic
Johnson, famous basketball player and HIV positive, has not infected
his wife not their daughter.
The correct therapy would be to dynamize the lymphocyte cells, with
the help of new enzymatic substance (active principles) that will
help phagocyte the viruses, and thus process the denatured substrate
in a function assisted by oxidation and reduction (the giving up of
protons). The virus would mutate into structure of lower molecular
magnitude and become negativized.
The Russian Metchnikoff, Nobel prize laureate in 1908,
thought that the microorganisms were phagocyted by special cells
(theory of cellular immunity).
The British scientist Wright adopted this theory and said,
“The power of phagocytosis of the
defending cells depends on its function by active substances”
and he used the word OPSONINE (OPSONÔ: “I prepare food for”).
Evidently enough, any therapy applied,
to be successful, will have to be combined with the administration
of active substances in certain amounts. If this is missing it will
cause a reduction in immune competence.
It is not the same to say:
“research should be centered on
finding out which are the active principles that can help
enzymatic function in order to regenerate the life of the
as to say “research should be
geared towards finding out which are the active principles
that can help enzymatic function, in order to regenerate
life in the cell”,
or to say “research should go in
search of inhibitory agents of cellular activity, in order
to stop the mission that nature itself has given it”
This would lead to a programming of an
early cellular death.
It is difficult to understand why some researchers recognize that
the enzymes are essential for the life of the cells of the receiving
organ, and, at the same time, other medical researchers devote all
their efforts to trying to find the “substrate” (exogenous) which is
most effective in paralyzing the natural function that the enzyme is
in charge of.
It is the obligation of doctors
to maintain life and cellular activity allowing the arrival of
native proteins to the cell, in order to make it work normally and,
especially in the case of those who are HIV positive, as they are
even more in need to maintaining the activity of those cells in
charge of contributing to immune-competence.
If the cells do not obtain sufficient energy through cellular
breathing, oxygen deficit can generate
lactic acid as a waste product.
HIV positive people should know which
are the symptoms of lactic acidosis, as it is and effect that
can be deadly.
It is difficult for me to understand how, on the one hand, some
researchers say that we should potentiate the selective creation of
defenses in our immunitary system, and on the other hand, medical
scientists are in favor of the administration of an inhibitory agent
in order to inactivate the receiving cell (which is also the
defending cell), blocking it with a view to avoid replication of the
The paralysis of the phagocyting
action of the substrate of the defending cell leads to the
programmed death of it (cellular apoptosis). Can it be beneficial to
program the killing of lymphocyte cells, defenders of the organism,
deliberately introducing the killer into the body?
As differences in opinion exist it is necessary to study this topic
in depth with a view to find the truth of the matter.
For repair of damaged mitochondrial and nuclear DNA to take
place it is mandatory to make the specific cell work in its optimum
pH. If this condition is not
present it will not be possible to stop the disease.
The optimum pH, or pH of maximum activity, is found around 6.5, and
therefore, if it is lowered to 3 with an acidizing agent the
unwanted enzyme will become inactive. If we look at the labels of
our foodstuffs we will certainly find some acidizing agent in most
of them, such as citric acid, which is used to this end.
Adequately fed cells will create immunity and give to the organism
the inherent capacity of curing itself.
Some common pH
Orange juice or apple
Saliva (cancer or AIDS patients)
Milk (fresh from the animal)
6,8 a 7,0
Blood, kidney, lung
Acid-basic balance in the organism:
this is the clue to health
The balance between acids and alkaline substances in the body is
critical for its good health. It is not possible to think seriously
about individualizing a diet without considering the effect on pH
balance in the body.
We are constantly generating acid waste
in the metabolism that should be neutralized or excreted for life to
be possible. Human beings, therefore, need a constant intake of
alkaline food in order to neutralize this constant acid generation.
Our life and health depend on the physiological power to maintain
the pH in our blood at around 7.35.
All live beings regulate their pH strictly in their intra and
extracellular solutions. The variation in the acid-basic property
can be seen reflected in the modulation of enzymatic speed and, in
humans, in the acidosis produced by acids resulting from metabolism.
This can cause cellular damage and death below pH 6.8, as can be
seen in diabetes.
If the pH in a human being varies below 7.35-7.45 the diet should be
pH in the saliva offers a way to evaluate the global pH balance in
the body. Saliva pH should be neuter, and due to its HCO3-
contents it has acid-neutralizing properties, and thus it plays an
important part in the hygiene of the mouth. Furthermore, the saliva
has other important roles.
Saliva pH is an indicator of the alkaline reserve in the body and of
cellular pH condition. The normal saliva pH should vary around 7.0 -
7.3, any other value being an indication of an illness.
Virtually all degenerative diseases, including cancer , heart
disease , osteoporosis, arthritis , kidney and gall stones, and
tooth decay are associated with excess acidity in the body.
Practically all degenerative illnesses such as cancer, heart
disease, osteoporosis, arthritis, kidney, liver and lung diseases,
diabetes and caries are associated with an excess of acidity in our
Acid-basic stability in the cellular tissue is an important factor
for health. Important deviations, produced in extreme situations
during serious illnesses are the cause of medical emergencies.
All disease symptoms can be reversible if very acid foods and
beverages are suppressed in our diet, and such symptoms will be
reactivated if they are consumed again.
IT IS NECESSARY TO KNOW WHICH IS THE pH OF OUR FOODSTUFFS AND WHICH
ARE THE ONES THAT ACT AS TRUE ALCALIZERS IN THE HUMAN BODY.
Adequately fed cells will create immunity and will give to our
organism the inherent capacity to cure itself.
Health is not something we should just dream of; it is something
that the human species can attain if the acid-basic balance is not
disturbed. A diet that in principle respects a neuter pH, not only
will avoid illnesses, but it will also cure already contracted
From the above, the basic function of pH regulation in biological
systems should be clear.
I acknowledge the important work by scientists studying the pH
(acid-basic balance) and enzymology. Without their magnificent
research and publications I would never have been able to associate
my empiric research with scientific research.
I believe that through empiric study
popular science can be connected to scientific knowledge.
the 'Bill & Melinda Gates Foundation'
Dear Mr. Perez,
Thank you for contacting the Bill & Melinda Gates Foundation.
While we appreciate how important
your request is, unfortunately, it is not within the current
giving priorities of the foundation. To remain focused on these
priorities, we must decline many worthwhile requests, leaving
other donors to support these causes.
The foundation’s Global Health
Program focuses on reducing the disease burden in the developing
world, with efforts concentrated in:
of and vaccine development for infectious diseases
such as HIV/AIDS, tuberculosis, and malaria, as well as
others that affect historically underserved populations
use, and sustainability of diagnostic tools and technologies
reproductive, and child health
raising awareness and promoting leadership for these issues
For more information about the
foundation’s Global Health Program, please visit
We appreciate your commitment to this work and wish you great
success with your endeavors.
Bill & Melinda Gates Foundation
I have received the recent above reply from the Foundation with
surprise and dismay.
In my message I very clearly
indicated that I am not interested in receiving funding from
you, but to find correspondents that might help me to
corroborate my ideas with respect to the origin and development
of some of the serious illnesses humankind suffers from.
I cannot understand why research of
such importance has not even sparked a minimal interest
on the part of the Foundation.
I regret to insist on asking for
your attention to my ideas, that, even if they go in
directions opposite to official research, at least
merit to be investigated.
I insist: VIH is not the cause of AIDS infection, and for
this reason researchers have not been able to find an effective
vaccine. There are several questions which still have not
received any answer, such as:
Why is there not
a single diabetic in the whole world who has been infected
Why are there
many heterosexual couples where one is HIV-positive and the
other one is not, who maintain sexual relations and there
has been no contagion?
Why are there
new-born babies of HIV-positive mothers who negativize
What about the
HIV-positive who have received spinal core transplant, and
who have negativized?
What about the
case of the homosexual patients in Los Angeles and San
Francisco, California, who supposedly contracted the illness
through sexual relations, and nothing was said about the
drug called “POPERS” which might have caused damage to the
spinal core and therefore has affected the lymphocytes,
transforming their molecular structure into viral protein (VIH)?
Would it not be
of interest to find the answer to such vital