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  by Mary West
 July 04, 2011
 
			from
			
			PreventDisease Website 
			
			Spanish version 
			While city living offers many amenities and advantages not found in 
			rural living, it might have a downside in the area of mental health.
 
			  
			City dwellers generally are more stressed and are at a higher risk 
			of developing mental illness than their rural counterparts. Although 
			scientists have been aware of this, they did not know the reason 
			why.  
			  
			A new study has revealed certain alterations in brain function 
			that could potentially provide the explanation,
			
			Time Healthland 
			reports.
 Previous research indicates that those who grow up in a city have a 
			two- to three-fold higher likelihood of developing schizophrenia. In 
			addition, earlier studies show that even after reaching adulthood, 
			city living raises the probability of contracting anxiety disorders 
			by 21% and mood illnesses, such as depression, by 39% compared with 
			rural dwellers.
 
 The new study has provided further enlightenment on the issue.
 
			  
			In an 
			international investigation published in 
			
			the journal Nature, 
			researchers at University of Heidelberg and McGill University report 
			that city dwellers or those who were raised in cities display 
			definite characteristics of activity in specific areas of the brain 
			that are not found in rural dwellers.  
			  
			The study pinpointed two areas 
			of the brain that seem to be involved in responding to stress.
 One structure of the brain that proved to be the culprit is 
			
			the amygdala, an area that regulates anxiety and fear. This part of the 
			brain is most often utilized in stressful or threatening situations 
			and the study suggests it is more sensitive in city dwellers.
 
 Another part of the brain the study implicated is the 
			
			anterior cingulate, a region that is a more global regulator of stress. The 
			research found that those raised in the city during their first 
			fifteen yeas of life showed a higher activation of this area. 
			Furthermore, this increased activation seems to be more permanent 
			than in those who moved to cities later in life, states Jens Pruessner, one of the investigation's coauthors.
 
			  
			He explains that 
			since the changes happen in an important period of development, 
			these individuals will become more alert to stressful situations for 
			the rest of their lives.
 Lead researcher, Andreas Meyer-Lindenberg, explains that although 
			the two brain structures are separate, they are linked by forming a 
			circuit. According to 
			
			Discovery News, he characterizes the findings 
			by stating that the areas of the brain connected to mental illness 
			were found to be hyperactive in city dwellers.
 
 In the study, researchers applied stress on volunteers while their 
			brains were being imaged by MRIs in order to determine which areas 
			of the brain were activated by stressful situations. The stress was 
			exerted by having the participants work difficult math problems, 
			either while they were under time pressure or while they were being 
			criticized by investigators for their poor performance.
 
 Following the application of stress, investigators compared the 
			results of the test with the population density of the area where 
			the participants were currently residing, as well as the place where 
			they were raised.
 
			  
			They found the degree of amygdala activation 
			increased with the size of their hometown, with it being highest in 
			the major metropolitan areas and lowest in the rural areas.
 Researchers are not suggesting that people vacate the city and move 
			to the country, but if the exact factors of city life responsible 
			for these brain changes are identified it could have implications 
			for city planning. They think the social aspects of urban living, 
			more so than factors such as noise or pollution, are the stressors 
			affecting the brain.
 
			  
			Future brain scanning investigations should 
			help researchers determine the causative agents in the urban 
			environment.
 
 
			Sources 
				
			 
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